Determination of total phenol, in-vitro antioxidant and anti-inflammatory activity of seeds and fruits of Zizyphus spina-christi grown in Oman

Alhakmani, Fatma; Khan, Shah Alam; Ahmad, Aftab

doi:10.12980/apjtb.4.2014apjtb-2014-0273

Cited by 57 publications

(29 citation statements)

References 21 publications

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“…These medicinal plants are reported to possess different pharmacological properties due to the presence of phytochemicals such as alkaloids, flavonoids, glycosides, tannins, and steroids. It is well-known that antioxidative properties of plants help to protect the body from free radical damage in cell structures, nucleic acids, lipids, proteins, and other body components and thereby reduce the risk and progression of many acute and chronic diseases like cancer, cardiovascular diseases, diabetes, and other metabolic syndromes [21]. The results of the present study on screening the phenolic and flavonoid contents and also the total antioxidant capacity confirmed that all three parts of T. cucumerina possess antioxidative properties.…”

Section: Discussionmentioning

confidence: 99%

Comparative Analysis of Nutritional and Bioactive Properties of Aerial Parts of Snake Gourd (Trichosanthes cucumerinaLinn.)

Liyanage

Nadeeshani

Jayathilake

et al. 2016

International Journal of Food Science

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The present investigation was carried out to determine the nutritional and functional properties of T. cucumerina. Water extracts of freeze dried flowers, fruits, and leaves of T. cucumerina were evaluated for their total phenolic content (TPC), total flavonoid content (TFC), antioxidant activity, α-amylase inhibitory activity, and fiber and mineral contents. Antioxidant activity, TPC, and TFC were significantly higher (P ≤ 0.05) in leaves than in flowers and fruits. A significant linear correlation was observed between the TPC, TFC, and antioxidant activities of plant extracts. Although, leaves and flower samples showed a significantly higher (P ≤ 0.05) amylase inhibitory activity than the fruit samples, the overall amylase inhibition was low in all three parts of T. cucumerina. Soluble and insoluble dietary fiber contents were significantly higher (P ≤ 0.05) in fruits than in flowers and leaves. Ca and K contents were significantly higher (P ≤ 0.05) in leaf followed by fruit and flower and Mg, Fe, and Zn contents were significantly higher (P ≤ 0.05) in leaves followed by flowers and fruits. In conclusion, T. cucumerina can be considered as a nourishing food commodity which possesses high nutritional and functional benefits for human health.

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Section: Discussionmentioning

confidence: 99%

Comparative Analysis of Nutritional and Bioactive Properties of Aerial Parts of Snake Gourd (Trichosanthes cucumerinaLinn.)

Liyanage

Nadeeshani

Jayathilake

et al. 2016

International Journal of Food Science

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“…Accordingly, The MIC values showed that the lowest level of antibacterial agent from the fruit extract of Ziziphus spina-christi that inhibit the growth of bacteria was ranging between (50-100 mg/ml). (Pawlowska et al, 2009), it was also reported that fruits of Ziziphus spina-christi have good antioxidant and anti-inflammatry effects and it was rich in bioactive phytochemicals such as tannins, steroids, flavonoids, alkaloids, glycosides and terpenoids (Alhakmani et al, 2014).…”

Section: Resultsmentioning

confidence: 99%

Antibacterial Activity of Fruit Methanol Extract of Ziziphus spina-christi from Sudan

Abdallah¹

2017

Int.J.Curr.Microbiol.App.Sci

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“…Anti-oxidant activity of Z. spina-christi extract has been reported in previous studies. Alhakmani et al (2014) showed that Z. spina-christi extract has significant anti-oxidant activity and can be used to prevent oxidative stress and related diseases. In the study conducted by Parsaeyan and Rezvani, (2014) Z. spina-christi injection into diabetic rats markedly reduced lipid per-oxidation and serum malondialdehyde level.…”

Section: Discussionmentioning

confidence: 99%

Effect of hydro-alcoholic extract of Ziziphus spina-christi against scopolamine-induced anxiety in rats

Setorki¹

2016

Bangladesh J Pharmacol

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The aim of this study was to observe the effect of Ziziphus spina-christi extract against anxiety related behavior induced by scopolamine. Rats were randomly divided into six groups, each group consists of eight rats. Vehicle group received distilled water, negative control received scopolamine (1 mg/kg) and positive control received diazepam (1 mg/mL). Experimental groups received Z. spina-christi extract (50, 100 and 200 mg/kg IP) 30 min after scopolamine injection. Anxiety related behaviors were assessed using the elevated plus maze. The rotarod test was used to evaluate motor coordination. Administration of Z. spina-christi extract (200 mg/kg) significantly increased the time spent in the open arm of elevated plus maze. The extract also reduced the percentage of closed arms entries and time spent in the closed arms. Different concentration of Z. spina-christi extract didn’t affect motor coordination and balance. Hydro-alcoholic extract of Z. spina-christi significantly ameliorate scopolamine-induced anxiety.Video clip<a href="https://youtube.com/v/LTHNppf_Euo">Elevated plus maze</a>: 1 min 58 sec

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Determination of total phenol, in-vitro antioxidant and anti-inflammatory activity of seeds and fruits of Zizyphus spina-christi grown in Oman

Cited by 57 publications

References 21 publications

Comparative Analysis of Nutritional and Bioactive Properties of Aerial Parts of Snake Gourd (Trichosanthes cucumerinaLinn.)

Comparative Analysis of Nutritional and Bioactive Properties of Aerial Parts of Snake Gourd (Trichosanthes cucumerinaLinn.)

Antibacterial Activity of Fruit Methanol Extract of Ziziphus spina-christi from Sudan

Effect of hydro-alcoholic extract of <i>Ziziphus spina-christi</i> against scopolamine-induced anxiety in rats

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