Determination of trace elements in urine by inductively coupled plasma-tandem mass spectrometry – Biomonitoring of adults in the German capital region

Schmied, Andy; Murawski, Aline; Kolossa-Gehring, Marike; Kujath, P.

doi:10.1016/j.chemosphere.2021.131425

Cited by 16 publications

(6 citation statements)

References 22 publications

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“…Asante et al (2012) made a 5-fold dilution with Milli-Q water to determine arsenic. Schmied et al (2021) made a 10-fold dilution with HNO 3 solution, 2% (v/v) and internal standard solution. Tong et al (2021) made a 10-fold dilution with HNO 3 solution, 1% (v/v).…”

Section: Discussionmentioning

confidence: 99%

Comparative study of two methods for rare earth elements analysis in human urine samples using inductively coupled plasma-mass spectrometry

Brouziotis

Giarra

Marano

et al. 2022

Front. Environ. Sci.

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The application of rare earth elements (REEs) in several areas, including high-tech technology, agriculture, medicine, and fuels, has made them an essential component of our everyday life. This extensive use of REEs in several technologies is expected to potentially impact human health. Even if several studies investigated the levels of REEs in human matrices, until now no standard method has been established for analyzing these elements in human matrices. The sample analysis should be of high quality, and the methods should be validated properly to ensure the quality of the procedure and traceability of the analytical data. In this research, we compared the validation and effectiveness of two different methods of sample preparation for human urine samples: a simple dilution of the sample (DIL) was compared with microwave assisted-acid decomposition (MIN) for tracing REE levels in human urine samples. The analysis was carried out by inductively coupled plasma mass spectrometry (ICP-MS). The working conditions have been set in high-sensitivity mode. Accuracy of the proposed method was evaluated by spiking the sample matrix with known concentrations of analyte standards. Both methods showed adequate precision of repeatability and intra-laboratory reproducibility, with the DIL method showing better precision of both repeatability and reproducibility than the MIN method. The CVr% values of repeatability range from 1.5 to 12% for the DIL and from 8.4 to 16% for the MIN method. The CVr% values of reproducibility range from 6.2–23% for the DIL and from 8.6 to 24% for the MIN method. REE recoveries for both methods were very close to 100%. Both methods proved to be effective for the determination of REE levels in human urine matrices.

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Section: Discussionmentioning

confidence: 99%

Comparative study of two methods for rare earth elements analysis in human urine samples using inductively coupled plasma-mass spectrometry

Brouziotis

Giarra

Marano

et al. 2022

Front. Environ. Sci.

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“…Urine samples are usually easy to collect, and their volume is not strictly limited. Moreover, urinalysis plays a key role in toxicology, 41 biomonitoring, 42 and occupational exposure studies 43,44 because many metabolites and most trace elements are excreted via this biological fluid.…”

Section: Selected Examples Of the Use Of Fa-icp-ms In The Analysis Of...mentioning

confidence: 99%

Flow techniques in the analysis of biological samples by inductively coupled plasma mass spectrometry – a review

Kowa,

Telk,

Wieczorek

2024

J. Anal. At. Spectrom.

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“…At the beginning of the experiment, all samples were thawed at 4 • C. Then, 1 mL of urine sample from the supernatant was added to a 15-mL CORNING centrifugal tube and acidified with 9 mL of 2% (v/v) nitric acid. Next, the resulting samples were digested by heating them at 40 • C in a water bath for one hour [44,45]. The final solution was filtered with a 0.22-µm filter (JINTENG, Tianjin, China; Polyethersulfone) for instrumental analysis.…”

Section: Sample Pretreatment and Instrument Analysismentioning

confidence: 99%

“…Correlation (Spearman) matrix for levels of 14 tested metals in Jingyuan County subjects; Table S6. Different age groups urinary median concentrations (µg/L) of metals including Ni, As, Se, Tl, Sr, Pb, Cu and Zn [ 3 , 21 , 39 , 45 , 46 , 49 , 53 , 54 , 83 , 84 , 85 , 86 ].…”

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confidence: 99%

Urinary Levels of 14 Metal Elements in General Population: A Region-Based Exploratory Study in China

Zhang,

Guo,

Hua

et al. 2023

Toxics

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Metal pollution may lead to a variety of diseases; for this reason, it has become a matter of public concern worldwide. However, it is necessary to use biomonitoring approaches to assess the risks posed to human health by metals. In this study, the concentrations of 14 metal elements in 181 urine samples obtained from the general population of Gansu Province, China, were analyzed using inductively coupled plasma mass spectrometry. Eleven out of fourteen target elements had detection frequencies above 85%, namely, Cr, Ni, As, Se, Cd, Al, Fe, Cu and Rb. The concentrations of most metal elements in the urine of our subjects corresponded to the medium levels of subjects in other regional studies. Gender exerted a significant influence (p < 0.05) on the concentrations of Tl, Rb and Zn. The concentrations of Ni, As, Pb, Sr, Tl, Zn, Cu and Se showed significant differences among different age groups and the age-related concentration trends varied among these elements. There were significant differences in the urine concentrations of Zn and Sr between those subjects in the group who were frequently exposed to soil (exposed soil >20 min/day) and those in the group who were not, indicating that people in regular contact with soil may be more exposed to metals. This study provides useful information for evaluating the levels of metal exposure among general populations.

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Determination of trace elements in urine by inductively coupled plasma-tandem mass spectrometry – Biomonitoring of adults in the German capital region

Cited by 16 publications

References 22 publications

Comparative study of two methods for rare earth elements analysis in human urine samples using inductively coupled plasma-mass spectrometry

Comparative study of two methods for rare earth elements analysis in human urine samples using inductively coupled plasma-mass spectrometry

Flow techniques in the analysis of biological samples by inductively coupled plasma mass spectrometry – a review

Urinary Levels of 14 Metal Elements in General Population: A Region-Based Exploratory Study in China

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