Determination of trace endocrine disruptors in ultrapure water for laboratory use by the yeast estrogen screen (YES) and chemical analysis (GC/MS)

Sanfilippo, Katy; Pinto, Barbara; Colombini, Maria Perla; Bartolucci, Ugo; Reali, Daniela

doi:10.1016/j.jchromb.2010.03.025

Cited by 29 publications

(9 citation statements)

References 24 publications

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“…The omnipresence of antiestrogenic pollutants was demonstrated by Sanfilippo et al [ 120 ] who, based on the yeast estrogen screen (YES) and chemical analysis (GC/MS), found antiestrogenic activity due to the presence of bis(2-ethylhexyl) phthalate (DEHP) in ultrapure water for laboratory use.…”

Section: Many Exposures Are Associated With Endocrine Disruptionmentioning

confidence: 99%

Endocrine-Disrupting Chemicals: Associated Disorders and Mechanisms of Action

Coster

Larebeke

2012

Journal of Environmental and Public Health

472

305

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The incidence and/or prevalence of health problems associated with endocrine-disruption have increased. Many chemicals have endocrine-disrupting properties, including bisphenol A, some organochlorines, polybrominated flame retardants, perfluorinated substances, alkylphenols, phthalates, pesticides, polycyclic aromatic hydrocarbons, alkylphenols, solvents, and some household products including some cleaning products, air fresheners, hair dyes, cosmetics, and sunscreens. Even some metals were shown to have endocrine-disrupting properties. Many observations suggesting that endocrine disruptors do contribute to cancer, diabetes, obesity, the metabolic syndrome, and infertility are listed in this paper. An overview is presented of mechanisms contributing to endocrine disruption. Endocrine disruptors can act through classical nuclear receptors, but also through estrogen-related receptors, membrane-bound estrogen-receptors, and interaction with targets in the cytosol resulting in activation of the Src/Ras/Erk pathway or modulation of nitric oxide. In addition, changes in metabolism of endogenous hormones, cross-talk between genomic and nongenomic pathways, cross talk with estrogen receptors after binding on other receptors, interference with feedback regulation and neuroendocrine cells, changes in DNA methylation or histone modifications, and genomic instability by interference with the spindle figure can play a role. Also it was found that effects of receptor activation can differ in function of the ligand.

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Section: Many Exposures Are Associated With Endocrine Disruptionmentioning

confidence: 99%

Endocrine-Disrupting Chemicals: Associated Disorders and Mechanisms of Action

Coster

Larebeke

2012

Journal of Environmental and Public Health

472

305

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“…These substances are found in many everyday objects and can easily enter our body ( De Coster & Van Larebeke, 2012 ). Sanfilippo et al (2010) identified trace endocrine disruptors, hormones (17-estradiol (E2), diethylstilbestrol (DES), 4-hydroxytamoxifen), phenolic compounds, and phthalates (bisphenol A (BPA), di (2-ethylhexyl) phthalate (DEHP), 4-octylphenol (OF), and 4- n -nonylphenol (4- n -NF)) in ultrapure water samples for laboratory use by gas chromatography-mass spectrometry (GC–MS). Carles et al (2021) studied and compared the effect of atrazine and nitrates on fetal growth and development; however, they found no evidence that atrazine-contaminated water had a negative impact on prenatal development.…”

Section: Introductionmentioning

confidence: 99%

Miniaturized solid-phase microextraction coupled with gas chromatography-mass spectrometry for determination of endocrine disruptors in drinking water

et al. 2022

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“…Therefore, the development of efficient analytical methods for its detection to prevent illegal usage is very important. Several analytical techniques have been used for the detection of DES, such as GC-MS [5][6][7], HPLC [8], LC-MS [9][10][11][12], electrochemical 2.-EXPERIMENTAL…”

Section: Introductionmentioning

confidence: 99%

Study of Dna-Diethylstilboestrol Interaction Using Graphene-Based Thin-Film Sensor and Uv-Vis Spectroscopy

Chen

et al. 2018

J. Chil. Chem. Soc.

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The graphene-modified glassy carbon electrode (Gr/GCE) was fabricated by casting graphene (Gr). Some electrochemical parameters for diethylstilbestrol (DES) detection, such as pH, scan rate, and accumulation time were discussed. The interaction of DES with DNA at a Gr/GCE was studied by electrochemical method and factors influencing the interaction were optimized. Under the optimized conditions, the results revealed that the peak current decreased and the peak potential shifted to the positive side after adding DNA into the solution containing DES. We deduced that the interaction of DES with DNA mainly is intercalation. The interaction of DES with DNA was studied by ultraviolet and visible (UV-Vis) absorption spectroscopy. Also, with the addition of DNA, hyperchromic effect and small red shifts were observed in its UV-VIS spectra upon addition of DNA, results indicated that the DES molecule intercalated into the DNA, and the complex of DES-DNA was formed.

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Determination of trace endocrine disruptors in ultrapure water for laboratory use by the yeast estrogen screen (YES) and chemical analysis (GC/MS)

Cited by 29 publications

References 24 publications

Endocrine-Disrupting Chemicals: Associated Disorders and Mechanisms of Action

Endocrine-Disrupting Chemicals: Associated Disorders and Mechanisms of Action

Miniaturized solid-phase microextraction coupled with gas chromatography-mass spectrometry for determination of endocrine disruptors in drinking water

Study of Dna-Diethylstilboestrol Interaction Using Graphene-Based Thin-Film Sensor and Uv-Vis Spectroscopy

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