Determination of Transaminase Activity of Serum Protein Fractions separated by Paper Electrophoresis

Changes in Certain Serum Enzym Activities Following Unilateral Extirpation of the Kidney and Partial Hepatectomy in Rats

“…In a previous work (with Varga, Leholay and Kovdcs, 10) like Sevela (8) and later Emmricli and Zimmermann (3) we also deter mined the GOT and aldolase-activity of protein fractions isolated from human serum in healthy subjects and in patients suffering from different diseases. These examinations showed that among the protein fractions of healthy subjects-within limits of normal values-as well as in patients with myocardial infarcts the highest GOT and aldolase-activity was in the albumin + alphaj-globulin fraction.…”

Differences in the Distribution of Glutamic Acid-Oxalacetic Acid Transaminase- and Aldolase-Activity among Serum Protein Fractions in Patients with Acute Myocardial Infarct and Hepatocellular Damage

“…Another peculiarity of our observations is that pathologically elevated protein fractions carry a greater part of the pathologically enhanced enzyme-activity. Sevela (1958) was the first who investigated the enzyme-acti vity of electrophoretically separated human serum protein frac tions. In both hepatocellular damage and myocardial infarction the highest GOT-activity was found to be present in the alpha, globulin and the glutamic acid-pyruvic acid transaminase in the beta globulin fraction.…”