2014
DOI: 10.1007/s10661-014-4015-z
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Determination of urinary levels of Bisphenol A in a Turkish population

Abstract: Bisphenol A (BPA) is one of the environmental endocrine disrupting chemicals that is widely used in common consumer products. The aim of this study was to report the total urinary BPA concentrations (free plus conjugated) in 200 urine samples (children: 57; male: 74; female: 69) obtained from residents of a Mediterranean city, Mersin. Analyses were performed by high-performance liquid chromatography tandem mass spectrometry (HPLC-MS/MS) and for assessing environmental exposure to free BPA and its major metabol… Show more

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Cited by 32 publications
(19 citation statements)
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“… 26 Human biomonitoring studies from different parts of the world consistently report higher urinary levels of BPA in children than in adults. 58 , 63 , 67 , 69 BPS levels were also higher in adolescents than in adults in a study of human exposures to BPS in Asia and the U.S. 30 These earlier findings are consistent with a higher xenobiotic intake of children and adolescents compared to adults due to a higher food intake and respiratory rate compared to adults; exposure to bisphenols via ingestion of household dust; more (dermal) contact with products containing BPA or its substitutes; and differences in the absorption, distribution, metabolism, and excretion of xenobiotics between children and adults. It is important to note that urinary levels of BPA were significantly higher in children compared to adults in the NHANES 2003–2004 population, 26 whereas median urinary levels of BPA in young adults (20–39 years old) were higher compared to those in children (6–11 years old) in the NHANES 2013–2014 population (1.47 vs 1.34 μg/L), possibly because of the ban of BPA in certain consumer products in the United States and other countries.…”
Section: Resultsmentioning
confidence: 99%
“… 26 Human biomonitoring studies from different parts of the world consistently report higher urinary levels of BPA in children than in adults. 58 , 63 , 67 , 69 BPS levels were also higher in adolescents than in adults in a study of human exposures to BPS in Asia and the U.S. 30 These earlier findings are consistent with a higher xenobiotic intake of children and adolescents compared to adults due to a higher food intake and respiratory rate compared to adults; exposure to bisphenols via ingestion of household dust; more (dermal) contact with products containing BPA or its substitutes; and differences in the absorption, distribution, metabolism, and excretion of xenobiotics between children and adults. It is important to note that urinary levels of BPA were significantly higher in children compared to adults in the NHANES 2003–2004 population, 26 whereas median urinary levels of BPA in young adults (20–39 years old) were higher compared to those in children (6–11 years old) in the NHANES 2013–2014 population (1.47 vs 1.34 μg/L), possibly because of the ban of BPA in certain consumer products in the United States and other countries.…”
Section: Resultsmentioning
confidence: 99%
“…A few studies have determined the BPA exposure level of individuals in Turkey. In 2014, mean urinary BPA values were 0.61 µg/g creatinine in 200 people from Mersin city (15). In a further study, BPA amounts were quantified for 26 female children aged 4-8 years having the endocrine condition Idiopathic Central Precocious Puberty (ICPP) and 21 healthy controls.…”
Section: Discussionmentioning
confidence: 99%
“…These studies have shown large variations between participants and studies, but very limited data are available for young children (13,14). To our knowledge, data regarding human exposure to BPA in Turkey are scarce (15). The primary aim of this study was to quantify exposure of preschool children to BPA.…”
Section: Introductionmentioning
confidence: 99%
“…[27][28][29] İdrar: Battal ve ark.nın, Türk toplumunda BFA seviyesini değerlendirdikleri çalışmada, idrar örnekleri kullanılmış ve idrarda 0,06-0,99 μg/g arasında değişen oranlarda BFA türevleri saptanmıştır. 30 Anne sütü: Özellikle yenidoğanların BFA maruziyetini değerlendirmek için yapılan çalışma-larda kullanılmış ve sağlıklı bir annenin sütünde ortalama 0,61 μg/mL oranında BFA saptanmıştır. 31…”
Section: Bi̇sfenol A'nin Kullanim Alanlariunclassified