Determination of Virulence Properties of Pathogenic Microorganisms in Vitro: State-of-Art

Abstract

Various methods for evaluation of virulence properties of causative agents of infectious diseases in vitro were analyzed: molecular-genetic, cultural-biochemical, immunologic, physiologic. Predominant use of molecular-genetic methods, expediency of a complex approach, relevance of search of novel informative parameters of virulence are noted. Study of biological properties of pathogens in vitro is the first screening stage of evaluation of their virulence.

Antimicrobial and Antiviral Respiratory Materials

“…Следует отметить, что результаты разных исследований трудно сравнивать, поскольку методы (см. обзоры [29,32]) и условия оценки патогенности микроорганизмов редко бывают одинаковыми.…”