Determination of α‐bisabolol and <scp>d</scp>‐panthenol in cosmetic products by gas chromatography

Andre, D.; Vérité, Philippe; Duclos, R.; Orecchioni, A. M.; Failly, F.

doi:10.1111/j.1467-2494.1991.tb00557.x

Cited by 5 publications

(1 citation statement)

References 2 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Extrato foliar: germacreno D, 1,8 cineol, elixeno, βcariofileno Extrato caulinar: α-bisabolol, elixeno, germacreno D, γmuuroleno α-bisabolol -anti-inflamatório, anti-irritante (Andre et al, 1991) Extrato foliar: atividade moderada contra H460 e K562. Flavonoides Extrato foliar: vitexina, derivado de luteolina, apigenina hexose-pentose Extrato caulinar: tilirosídeo, flavonol p-cumaroil glicosídeo, quercetina p-cumaroil glucosídeo vitexina -hipotensora, anti-inflammatória e antiespasmódica e antiproliferativa Linhagens celulares: U251 -glioma; MCF-7 -mama; H460 -pulmão, tipo não pequenas células; PC-3 -próstata; OVCAR-3 -ovário; K562 -leucemia.…”

Section: óLeos Voláteisunclassified

Análise fitoquímica e atividade antiproliferativa de espécies nativas de Croton L. (Euphorbiaceae)

Savietto¹

View full text Add to dashboard Cite

Depois de todo o trabalho, como é bom poder agradecer! Agradeço à Profa. Déborah, pela orientação dada nestes anos de mestrado, por compartilhar seu conhecimento e por ter me acolhido como aluna, mesmo sabendo desde o início que cedo ou tarde eu partiria em direção a outros desafios. Aos profs. Salatino, Maria Luiza e Cláudia Furlan pelos valiosos conhecimentos, aulas, broncas e festas! Aprendi muito com vocês. Também agradeço a colaboração da Profa. Giusepinna Negri.

show abstract

Section: óLeos Voláteisunclassified

Análise fitoquímica e atividade antiproliferativa de espécies nativas de Croton L. (Euphorbiaceae)

Savietto¹

View full text Add to dashboard Cite

show abstract

(−)-α-Bisabolol reduces orofacial nociceptive behavior in rodents

Melo

Duailibe

Pessoa

et al. 2016

Naunyn-Schmiedeberg's Arch Pharmacol

View full text Add to dashboard Cite

The purposes of this study were to evaluate the anti-nociceptive effect of oral and topical administration of (-)-α-bisabolol (BISA) in rodent models of formalin- or cinnamaldehyde-induced orofacial pain and to explore the inhibitory mechanisms involved. Orofacial pain was induced by injecting 1.5% formalin into the upper lip of mice (20 μL) or into the temporomandibular joint (TMJ) of rats (50 μL). In another experiment, orofacial pain was induced with cinnamaldehyde (13.2 μg/lip). Nociceptive behavior was proxied by time (s) spent rubbing the injected area and by the incidence of head flinching. BISA (100, 200, or 400 mg/kg p.o. or 50, 100, or 200 mg/mL topical) or vehicle was administered 60 min before pain induction. The two formulations (lotion and syrup) were compared with regard to efficacy. The effect of BISA remained after incorporation into the formulations, and nociceptive behavior decreased significantly in all tests. The high binding affinity observed for BISA and TRPA1 in the molecular docking study was supported by in vivo experiments in which HC-030031 (a TRPA1 receptor antagonist) attenuated pain in a manner qualitatively and quantitatively similar to that of BISA. Blockers of opioid receptors, NO synthesis, and K ATP channels did not affect orofacial pain, nor inhibit the effect of BISA. In conclusion, BISA had a significant anti-nociceptive effect on orofacial pain. The effect may in part be due to TRPA1 antagonism. The fact that the effect of BISA remained after incorporation into oral and topical formulations suggests that the compound may be a useful adjuvant in the treatment of orofacial pain.

show abstract

Direct determination of d-panthenol and salt of pantothenic acid in cosmetic and pharmaceutical preparations by differential pulse voltammetry

Wang

Tseng

2001

Analytica Chimica Acta

View full text Add to dashboard Cite

Determination of α‐bisabolol and d‐panthenol in cosmetic products by gas chromatography

Cited by 5 publications

References 2 publications

Análise fitoquímica e atividade antiproliferativa de espécies nativas de Croton L. (Euphorbiaceae)

Análise fitoquímica e atividade antiproliferativa de espécies nativas de Croton L. (Euphorbiaceae)

(−)-α-Bisabolol reduces orofacial nociceptive behavior in rodents

Direct determination of d-panthenol and salt of pantothenic acid in cosmetic and pharmaceutical preparations by differential pulse voltammetry

Contact Info

Product

Resources

About