Determining factors for the nano-biocompatibility of cobalt oxide nanoparticles: proximal discrepancy in intrinsic atomic interactions at differential vicinage

Verma, Suresh K.; Panda, Pritam Kumar; Kumari, Puja; Patel, Paritosh; Arunima, Aryashree; Jha, Eealisha; Husain, Saddam; Prakash, Ravi; Hergenröder, Roland; Mishra, Yogendra Kumar; Ahuja, Rajeev; Varma, Rajender S.; Suar, Mrutyunjay

doi:10.1039/d1gc00571e

Cited by 48 publications

(23 citation statements)

References 72 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Oxidative stress analysis in Fe 3 O 4 and α-Fe 2 O 3 /C exposed embryos was done by staining of treated and untreated embryos using 1.25 mg/L 2′,7′-dichlorofluorescin diacetate (H 2 DCFDA) dye for 20 min in dark [ 12 ]. The embryos were exposed as mentioned in protocol for biocompatibility assays.…”

Section: Methodsmentioning

confidence: 99%

“…Apoptosis analysis of exposed and unexposed embryos was done by Acridine orange staining as described by Verma et al. [ 12 ]. In brief, untreated and treated zebrafish embryos with Fe 3 O 4 and α-Fe 2 O 3 /C were stained with 5 μg/mL acridine orange (AO) dissolved in HF for 20 min followed by washing with HF buffer for removal of extra stains.…”

Section: Methodsmentioning

confidence: 99%

“…Magnetic nanoparticles (MNPs) such as iron oxide, cobalt oxide, and nickel-based nanomaterials have been investigated for the supercapacitor designing purpose. These nanoparticles have been reported to be deployed for many physical and environmental applications [ 12 ]. However, rigorous investigations at the laboratory scale and the use of the nanomaterials at the industrial scale have raised concern over their after-usage accumulation in the environment followed by their toxicological impacts.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Altered electrochemical properties of iron oxide nanoparticles by carbon enhance molecular biocompatibility through discrepant atomic interaction

Verma

Thirumurugan

Panda

et al. 2021

Materials Today Bio

Self Cite

View full text Add to dashboard Cite

Recent advancement in nanotechnology seeks exploration of new techniques for improvement in the molecular, chemical, and biological properties of nanoparticles. In this study, carbon modification of octahedral-shaped magnetic nanoparticles (MNPs) was done using two-step chemical processes with sucrose as a carbon source for improvement in their electrochemical application and higher molecular biocompatibility. X-ray diffraction analysis and electron microscopy confirmed the alteration in single-phase octahedral morphology and carbon attachment in Fe 3 O 4 structure. The magnetization saturation and BET surface area for Fe 3 O 4 , Fe 3 O 4 /C, and α-Fe 2 O 3 /C were measured as 90, 86, and 27 emu/g and 16, 56, and 89 m 2 /g with an average pore size less than 7 nm. Cyclic voltammogram and galvanostatic charge/discharge studies showed the highest specific capacitance of carbon-modified Fe 3 O 4 and α-Fe 2 O 3 as 213 F/g and 192 F/g. The in vivo biological effect of altered physicochemical properties of Fe 3 O 4 and α-Fe 2 O 3 was assessed at the cellular and molecular level with embryonic zebrafish. Mechanistic in vivo toxicity analysis showed a reduction in oxidative stress in carbon-modified α-Fe 2 O 3 exposed zebrafish embryos compared to Fe 3 O 4 due to despaired influential atomic interaction with sod1 protein along with significant less morphological abnormalities and apoptosis. The study provided insight into improving the characteristic of MNPs for electrochemical application and higher biological biocompatibility.

show abstract

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Altered electrochemical properties of iron oxide nanoparticles by carbon enhance molecular biocompatibility through discrepant atomic interaction

Verma

Thirumurugan

Panda

et al. 2021

Materials Today Bio

Self Cite

View full text Add to dashboard Cite

show abstract

“…Though nanomaterials and virus capsid are in the establishment as a drug carrier, the utility and production depend on the physical parameters and chemistry. To use virus capsid, the isolation, purification and deployment require new technologies and methods and a lot of quality assessment to maximize extracted quantities; however, the synthetic and green method available for the nanomaterial's synthesis gives them the benefit ahead [ 89 , 144 , 157 , 158 ]. Discussing the pros and cons of using nanomaterials and viral capsid, the leverage of merits bends in the direction of the viral capsid, owing to being biological in origin.…”

Section: Viral Capsids and Other Nanomaterials As Drug Carriersmentioning

confidence: 99%

The Viral Capsid As Novel Nanomaterials for Drug Delivery

Aljabali

Hassan²,

Pabari

et al. 2021

Future Sci. OA

Self Cite

View full text Add to dashboard Cite

The purpose of this review is to highlight recent scientific developments and provide an overview of virus self-assembly and viral particle dynamics. Viruses are organized supramolecular structures with distinct yet related features and functions. Plant viruses are extensively used in biotechnology, and virus-like particulate matter is generated by genetic modification. Both provide a material-based means for selective distribution and delivery of drug molecules. Through surface engineering of their capsids, virus-derived nanomaterials facilitate various potential applications for selective drug delivery. Viruses have significant implications in chemotherapy, gene transfer, vaccine production, immunotherapy and molecular imaging.

show abstract

“…The fabricated microwave absorbing materials can essentially promote our health by loading them into textiles, building materials, and dyes, protecting us against harmful radiations. One of the essential aspects to take into account is the biocompatibility of the employed materials in microwave absorbers, diminishing secondary health damages 7 , 8 . The achieved results manifest that the size of carbon-based materials and their functional groups are the crucial factors influencing their biocompatibility 9 , 10 .…”

Section: Introductionmentioning

confidence: 99%

Architecting functionalized carbon microtube/carrollite nanocomposite demonstrating significant microwave characteristics

Peymanfar

Selseleh-Zakerin²,

Ahmadi³

et al. 2021

Sci Rep

View full text Add to dashboard Cite

Biomass-derived materials have recently received considerable attention as lightweight, low-cost, and green microwave absorbers. On the other hand, sulfide nanostructures due to their narrow band gaps have demonstrated significant microwave characteristics. In this research, carbon microtubes were fabricated using a biowaste and then functionalized by a novel complementary solvothermal and sonochemistry method. The functionalized carbon microtubes (FCMT) were ornamented by CuCo2S4 nanoparticles as a novel spinel sulfide microwave absorber. The prepared structures illustrated narrow energy band gap and deposition of the sulfide structures augmented the polarizability, desirable for dielectric loss and microwave attenuation. Eventually, the architected structures were blended by polyacrylonitrile (PAN) to estimate their microwave absorbing and antibacterial characteristics. The antibacterial properties against Gram-negative Escherichia coli (E. coli) and Gram-positive Staphylococcus aureus (S. aureus) were scrupulously assessed. Noteworthy, the maximum reflection loss (RL) of the CuCo2S4/PAN with a thickness of 1.75 mm was 61.88 dB at 11.60 GHz, while the architected FCMT/PAN composite gained a broadband efficient bandwidth as wide as 7.91 GHz (RL > 10 dB) and 3.25 GHz (RL > 20 dB) with a thickness of 2.00 mm. More significantly, FCMT/CuCo2S4/PAN demonstrated an efficient bandwidth of 2.04 GHz (RL > 20 dB) with only 1.75 mm in thickness. Interestingly, FCMT/CuCo2S4/PAN and CuCo2S4/PAN composites demonstrated an electromagnetic interference shielding efficiency of more than 90 and 97% at the entire x and ku-band frequencies, respectively.

show abstract

Determining factors for the nano-biocompatibility of cobalt oxide nanoparticles: proximal discrepancy in intrinsic atomic interactions at differential vicinage

Abstract: Abounding use of cobalt oxide nanoparticles (Co3O4) requires a detailed understanding of their environmental and biomedical nanotoxicity and an eminent solution to the associated hazards; molecular and atomic aspects of...

Cited by 48 publications

References 72 publications

Altered electrochemical properties of iron oxide nanoparticles by carbon enhance molecular biocompatibility through discrepant atomic interaction

Altered electrochemical properties of iron oxide nanoparticles by carbon enhance molecular biocompatibility through discrepant atomic interaction

The Viral Capsid As Novel Nanomaterials for Drug Delivery

Architecting functionalized carbon microtube/carrollite nanocomposite demonstrating significant microwave characteristics

Contact Info

Product

Resources

About