Deterministic Risk Assessment of Trichothecenes Type A Mycotoxin Through Cereal Intake for Koreans

Abstract

This research was conducted to estimate the dietary exposure of trichothescene type A mycotoxins (T-2 and HT-2 toxin) and to assess the related risk for the Korean populations from the intake of cereals. The deterministic approach was used to estimate the dietary exposure. The amounts of trichothescene type A mycotoxins in 115 samples of cereals were determined by LC-MS/MS. The levels of trichothescene type A mycotoxins (T-2 and HT-2 toxin) in cereals ranged from: N.D.-37.10 ug/kg for T-2 toxin and N.D.-5.43 μg/kg for HT-2 toxin. The mean and 95th percentile for exposure to the dietary sum of trichothescene type A mycotoxins were 0.57 ng/kg b.w/day (LB), 1.39 ng/kg b.w/day (MB), 2.20 ng/kg b.w/day (UB), and 11.06 ng/kg b.w/day (LB), 13.95 ng/kg b.w/day (MB), 16.87 ng/kg b.w/day (UB) corresponding to 0.57 to 2.20% of the Total Dietary Intake (TDI) for the mean exposure and 11.06 to 16.87% of TDI for the 95th percentile exposure. Therefore, the overall exposure level of trichothescene type A mycotoxins for Koreans from cereal intake is unlikely to cause concerns to human health.