Mantle-induced dynamic topography (i.e., subsidence and uplift) has been increasingly recognized as an important process in foreland basin development. However, characterizing and distinguishing the effects (i.e., location, extent and magnitude) of dynamic topography in ancient foreland basins remains challenging because the spatio-temporal footprint of dynamic topography and flexural topography (i.e., generated by topographic loading) can overlap. This study employs 3D flexural backstripping of Upper Cretaceous strata in the central part of the North American Cordilleran foreland basin (CFB) to better quantify the effects of dynamic topography. The extensive stratigraphic database and good age control of the CFB permit the regional application of 3D flexural backstripping in this basin for the first time. Dynamic topography started to influence the development of the CFB during the late Turonian to middle Campanian (90.2-80.2 Ma) and became the dominant subsidence mechanism during the middle to late Campanian (80.2-74.6 Ma). The area influenced by >100 m dynamic subsid-ence is approximately 400 by 500 km, within which significant (>200 m) dynamic subsidence occurs in an irregular-shaped (i.e., lunate) subregion. The maximum magnitude of dynamic subsidence is 300 ± 100 m based on the 80.2-74.6 Ma tectonic subsidence maps. With the maximum magnitude of dynamic uplift being constrained to be 200-300 m, the gross amount of dynamic topography in the Late Cretaceous CFB is 500-600 m. Although the location of dynamic subsidence revealed by tectonic subsidence maps is generally consistent with isopach map trends, tectonic subsidence maps developed through 3D flexural backstripping provide more accurate constraints of the areal extent, magnitude and rate of dynamic topography (as well as flexural topography) in the CFB through the Late Cretaceous. This improved understanding of dynamic topography in the CFB is critical for refining current geodynamic models of foreland basins and understanding the surface expression of mantle processes.