Developing a newborn rat model of meningitis without concomitant bacteremia by intraventricular injection of K1 (-) Escherichia coli

Abstract

25Neonatal meningitis caused by Escherichia coli results in high mortality and neurological 26 disabilities, and the concomitant systemic bacteremia confounds its mortality and brain 27 injury. This study developed an experimental model of neonatal meningitis without