Developing an alcoholic‐assisted dispersive liquid–liquid microextraction for extraction of pentachlorophenol in water

Abstract

Optimization of alcoholic-assisted dispersive liquid-liquid microextraction of pentachlorophenol (PCP) and determination of it with high-performance liquid chromatography (UV-Vis detection) was investigated. A Plackett-Burman design and a central composite design were applied to evaluate the alcoholic-assisted dispersive liquid-liquid microextraction procedure. The effect of seven parameters on extraction efficiency was investigated. The factor studied were type and volume of extraction and dispersive solvents, amount of salt, and agitation time. According to Plackett-Burman design results, the effective parameters were type and volume of extraction solvent and agitation time. Next, a central composite design was applied to obtain optimal condition. The optimized conditions were obtained at 170-μL 1-octanol and 5-min agitation time. The enrichment factor of PCP was 242 with limits of detection of 0.04 μg L(-1). The linearity was 0.1-100 μg L(-1) and the extraction recovery was 92.7%. RSD for intra and inter day of extraction of PCP were 4.2% and 7.8%, respectively for five measurements. The developed method was successfully applied for the determination of PCP in environmental water samples.

A perspective on the growth of chemometrics in Iran: a glance into activities between 2005 and 2012

“…Among them, 340 papers are categorized in the subject field of chemistry. The multivariate statistical methods are most used in chromatography, spectrophotometry, electrochemistry, and applied chemistry . Our search showed that there are only eight documents in the field of experimental design published by Iranian chemists from 2000 to 2004.…”

Evaluation of alcoholic-assisted dispersive liquid-liquid microextraction of bisphenol a in water samples using an experimental design

“…One of the main disadvantages associated with DLLME, however, is that it uses toxic extraction solvents. In order to develop the applicability of the DLLME procedure, the alcoholic-assisted dispersive liquid-liquid microextraction (AA-DLLME) method was introduced in our laboratory [28]. The basic criteria in AA-DLLME for selection of alcoholic solvents as extraction and dispersive solvents are their less toxicity and environmental greenness.…”