“…Collaborative Care models for the treatment of depression in primary care, such as the Translating Initiatives for Depression into Effective Solutions (TIDES) model [43][44][45] , have demonstrated significant improvements in depression treatment completion rates in numerous randomized controlled trials [46][47][48][49][50] . Central to TIDES is the "Care Manager," typically a nurse supervised by a psychiatrist, who provides ongoing support for anti-depressant medication adherence in primary care and conducts clinical outcomes assessments to guide PCPs' decision-making regarding mental health treatment 43,51 .…”