Developing effective strategies to optimize physical activity and cardiorespiratory fitness in the long Covid population- The need for caution and objective assessment

Faghy, Mark A.; Duncan, Rae; Hume, Emily; Gough, Lewis; Roscoe, Clare; Laddu, Deepika; Arena, Ross; Asthon, Ruth E.M.; Dalton, Caroline

doi:10.1016/j.pcad.2024.03.003

Cited by 4 publications

(1 citation statement)

References 88 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The findings of clinical severity types and the fluctuating nature of the condition have widespread implications for self-management and the interventions provided by healthcare professionals, as well as the support provided by carers and family members. There is established evidence for PEM or PESE in the literature as a hallmark finding in LC and other post-viral illness [26][27][28]. Relapse can be triggered by physical, cognitive, or emotional exertion, and evidence suggests that cognitive and emotional exertion can be responsible in equal measure to physical exertion.…”

Section: Discussionmentioning

confidence: 99%

Long COVID Clinical Severity Types Based on Symptoms and Functional Disability: A Longitudinal Evaluation

Sivan,

Smith,

Osborne

et al. 2024

JCM

View full text Add to dashboard Cite

Background: Long COVID (LC) is a multisystem clinical syndrome with functional disability and compromised overall health. Information on LC clinical severity types is emerging in cross-sectional studies. This study explored the pattern and consistency of long COVID (LC) clinical severity types over time in a prospective sample. Methods: Participants with LC completed the condition-specific outcome measure C19-YRSm (Yorkshire Rehabilitation Scale modified version) at two assessment time points. A cluster analysis for clinical severity types was undertaken at both time points using the k-means partition method. Results: The study included cross-sectional data for 759 patients with a mean age of 46.8 years (SD = 12.7), 69.4% females, and a duration of symptoms of 360 days (IQR 217 to 703 days). The cluster analysis at first assessment revealed three distinct clinical severity type clusters: mild (n = 96), moderate (n = 422), and severe (n = 241). Longitudinal data on 356 patients revealed that the pattern of three clinical severity types remained consistent over time between the two assessments, with 51% of patients switching clinical severity types between the assessments. Conclusions: This study is the first of its kind to demonstrate that the pattern of three clinical severity types is consistent over time, with patients also switching between severity types, indicating the fluctuating nature of LC.

show abstract

Section: Discussionmentioning

confidence: 99%

Long COVID Clinical Severity Types Based on Symptoms and Functional Disability: A Longitudinal Evaluation

Sivan,

Smith,

Osborne

et al. 2024

JCM

View full text Add to dashboard Cite

show abstract

Attenuating post-exertional malaise in Myalgic encephalomyelitis/chronic fatigue syndrome and long-COVID: Is blood lactate monitoring the answer?

Faghy,

Ashton,

McNelis

et al. 2024

Current Problems in Cardiology

View full text Add to dashboard Cite

Personalised Health Behaviour Support Programme in Adults With Post‐COVID Syndrome: A Randomised, Controlled Pilot Feasibility Trial

Armstrong,

Owen,

Van Niekerk

et al. 2024

Health Expectations

View full text Add to dashboard Cite

BackgroundWe investigated whether a novel 8‐week personalised health behaviour support programme, focusing on the stability of symptoms and strategies to improve activities of daily living, was feasible and acceptable in adults with post‐COVID syndrome.MethodsIn this randomised, controlled, pilot feasibility trial, 32 adults with post‐COVID syndrome (continued symptoms for ≥ 12 weeks) were randomised 1:1 to receive personalised health behaviour support (self‐reported physical activity and symptom diaries, plus seven one‐to‐one remotely delivered personalised self‐management support sessions), once weekly for 8‐weeks, or usual care (referral to online ‘your COVID‐19 recovery’ programme). The primary outcome was the feasibility of recruiting and randomising adults with post‐COVID syndrome. The secondary outcomes were to assess the acceptability and safety of the intervention and various outcome measures.ResultsOf the 48 adults who expressed interest in the study, 32 (67%) were eligible and completed the baseline assessment. All 32 adults were willing to be randomised to either the personalised health behaviour support programme (n = 17) or usual care (n = 15) and 27 (age: 45 ± 12 years) adults completed follow‐up at 9 weeks. The intervention was deemed feasible, with high adherence (92% and 94% completion rates for the physical activity and symptom diaries, respectively) and excellent acceptability rates (94% ‘liked the intervention a lot’). The intervention was deemed safe, with no symptom exacerbations reported.ConclusionAn 8‐week personalised health behaviour support programme was feasible for adults with post‐COVID syndrome, with good adherence and acceptability rates. Early pilot data from this small sample also suggests meaningful improvements in physical activity, fatigue and respiratory symptoms.Patient or Public ContributionPeople living with post‐COVID syndrome were involved from the outset with the study design, review of study documentation and interpretation of the data following completion. Furthermore, several participants have supported the local dissemination of findings following the completion of the study.

show abstract

Developing effective strategies to optimize physical activity and cardiorespiratory fitness in the long Covid population- The need for caution and objective assessment

Cited by 4 publications

References 88 publications

Long COVID Clinical Severity Types Based on Symptoms and Functional Disability: A Longitudinal Evaluation

Long COVID Clinical Severity Types Based on Symptoms and Functional Disability: A Longitudinal Evaluation

Attenuating post-exertional malaise in Myalgic encephalomyelitis/chronic fatigue syndrome and long-COVID: Is blood lactate monitoring the answer?

Personalised Health Behaviour Support Programme in Adults With Post‐COVID Syndrome: A Randomised, Controlled Pilot Feasibility Trial

Contact Info

Product

Resources

About