Developing multispecies quorum-sensing modulators based on the Streptococcus mitis competence-stimulating peptide

Milly, Tahmina A.; Renshaw, Clay P.; Tal-Gan, Yftah

doi:10.1016/j.jbc.2023.105448

Journal of Biological Chemistry

2023

DOI: 10.1016/j.jbc.2023.105448

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Developing multispecies quorum-sensing modulators based on the Streptococcus mitis competence-stimulating peptide

Tahmina A. Milly,

Clay P. Renshaw,

Yftah Tal-Gan

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2024

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Metabolic and Lipid Biomarkers for Pathogenic Algae, Fungi, Cyanobacteria, Mycobacteria, Gram-Positive Bacteria, and Gram-Negative Bacteria

Wood

2024

Metabolites

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The utilization of metabolomics and lipidomics analytical platforms in the study of pathogenic microbes is slowly expanding. These research approaches will significantly contribute to the establishment of microbial metabolite and lipid databases of significant value to all researchers in microbiology. In this review, we present a high-level overview of some examples of biomarkers that can be used to detect the presence of microbes, monitor the expansion/decline of a microbe population, and add to our understanding of microbe biofilms and pathogenicity. In addition, increased knowledge of the metabolic functions of pathogenic microbes can contribute to our understanding of microbes that are utilized in diverse industrial applications. Our review focuses on lipids, secondary metabolites, and non-ribosomal peptides that can be monitored using electrospray ionization high-resolution mass spectrometry (ESI-HRMS).

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Metabolic and Lipid Biomarkers for Pathogenic Algae, Fungi, Cyanobacteria, Mycobacteria, Gram-Positive Bacteria, and Gram-Negative Bacteria

Wood

2024

Metabolites

View full text Add to dashboard Cite

show abstract

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Developing multispecies quorum-sensing modulators based on the Streptococcus mitis competence-stimulating peptide

Cited by 1 publication

References 42 publications

Metabolic and Lipid Biomarkers for Pathogenic Algae, Fungi, Cyanobacteria, Mycobacteria, Gram-Positive Bacteria, and Gram-Negative Bacteria

Metabolic and Lipid Biomarkers for Pathogenic Algae, Fungi, Cyanobacteria, Mycobacteria, Gram-Positive Bacteria, and Gram-Negative Bacteria

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