The world of entrepreneurs in Malaysia has been led by Muslims. This has contributed to the growth of the Muslim economy. There are issues of failure in business management based on Islamic spiritual values. Spirituality is the process of the internal development of the soul. In Islam, it is based on faith in life, believing and trust in Allah Almighty, while application of the tauhid paradigm in both in this world and hereafter are related affairs. The purpose of the study is to analyze the potential of spiritual elements in the success of Muslim entrepreneurs. In this article, the researchers applied the Systematic Literature Review methodology, which focuses on research objectives. This article uses three (3) steps to analyze selected articles, i.e., by identification, screening, and eligibility. The outcome of this study had established five (5) journal articles that discussed spiritual elements that played an important role in the success of Muslim entrepreneurs, based on religious practices and values that were applied in entrepreneurship. The analysis found that the belief in Allah and the practice of religious values helped to enhance confidence and build the strong personality and traits of successful entrepreneurs. This is contributed by the elements of gratitude (Shukr), approval (riḍā), and reliance (tawakkal) after the best effort. Therefore, this study is expected to contribute to the research on entrepreneurship in Malaysia, especially for the Muslim community.