Developing the medicinal plants sector in northern India: challenges and opportunities

Kala, Chandra Prakash; Dhyani, P. P.; Sajwan, Bikram Singh

doi:10.1186/1746-4269-2-32

Cited by 336 publications

(219 citation statements)

References 29 publications

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“…43 Kala and co-workers have provided an evaluation of the problems and some remedies for medicinal plant development in northern India, and the impact on local economies. 37 An assessment of 49 medicinal plants in the Himalayan region used for 34 different indications estimated potential yearly needs and determined that 24 plants were regarded as being in annual short supply. 37 In other studies, 44 the population density of threatened medicinal plant species in seven protected areas in the Indian Himalayas was assessed through interviewing 83 Tibetan and 55 Ayurvedic healers.…”

Section: Endangered and Threatened Medicinal Plant Speciesmentioning

confidence: 99%

“…37 An assessment of 49 medicinal plants in the Himalayan region used for 34 different indications estimated potential yearly needs and determined that 24 plants were regarded as being in annual short supply. 37 In other studies, 44 the population density of threatened medicinal plant species in seven protected areas in the Indian Himalayas was assessed through interviewing 83 Tibetan and 55 Ayurvedic healers. Sixty medicinal plants used for 45 different ailments were found to be threatened, and 32 of these were endemic to the Himalayan region.…”

Section: Endangered and Threatened Medicinal Plant Speciesmentioning

confidence: 99%

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Sustainable drugs and global health care

Cordell¹

2009

Quím. Nova

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Each day, Earth's finite resources are being depleted for energy, for material goods, for transportation, for housing, and for drugs. As we evolve scientifically and technologically, and as the population of the world rapidly approaches 7 billion and beyond, among the many issues with which we are faced is the continued availability of drugs for future global health care. Medicinal agents are primarily derived from two sources, synthetic and natural, or in some cases, as semi-synthetic compounds, a mixture of the two. For the developed world, efforts have been initiated to make drug production "greener", with milder reagents, shorter reaction times, and more efficient processing, thereby using less energy, and reactions which are more atom efficient, and generate fewer by-products. However, most of the world's population uses plants, in either crude or extract form, for their primary health care. There is relatively little discussion as yet, about the long term effects of the current, non-sustainable harvesting methods for medicinal plants from the wild, which are depleting these critical resources without concurrent initiatives to commercialize their cultivation. To meet future public health care needs, a paradigm shift is required in order to adopt new approaches using contemporary technology which will result in drugs being regarded as a sustainable commodity, irrespective of their source. In this presentation, several approaches to enhancing and sustaining the availability of drugs, both synthetic and natural, will be discussed, including the use of vegetables as chemical reagents, and the deployment of integrated strategies involving information systems, biotechnology, nanotechnology, and detection techniques for the development of medicinal plants with enhanced levels of bioactive agents.

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Section: Endangered and Threatened Medicinal Plant Speciesmentioning

confidence: 99%

Section: Endangered and Threatened Medicinal Plant Speciesmentioning

confidence: 99%

Sustainable drugs and global health care

Cordell¹

2009

Quím. Nova

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“…The economic exploitation of aromatic and medicinal species has increased due to a renewed interest in the use of natural compounds (Kala, Dhyani, & Sajwan, 2006). These metabolites can be obtained either from wild field-growing or cultivated plants.…”

Section: Introductionmentioning

confidence: 99%

A Rapid and Efficient Protocol for Clonal Propagation of Phenolic-Rich Lavandula multifida

Zuzarte¹,

Dinis²,

Salgueiro³

et al. 2015

JAS

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Lavandula multifida (fernleaf lavender) grows in confined regions of Portugal. This species is known for its interesting chemical profile, rich in phenolic compounds, and significant antifungal and anti-inflammatory properties, making it an interesting plant for industrial exploitation and justifying alternative propagation methods. Therefore, the present study aims the development of an efficient protocol for large scale propagation of this species, assuring plant uniformity and aiming a sustainable industrial exploitation with preservation of natural resources.In vitro cultures were established on Murashige and Skoog medium (MS) with different concentrations of benzyladenine (BA) and zeatin (ZEA). Best multiplication rates (6.14 shoots per explant) were achieved using MS supplemented with 1.0 mg/L ZEA and rooting occurred spontaneously on the propagation medium avoiding additional rooting steps. Moreover, plants flowered during the acclimatization phase, confirming a more rapid in vitro development and shorter breeding cycle. This is a very interesting aspect for essential oil extraction. Trichome morphology was examined by scanning electron microscopy and the secretion analyzed through histochemical tests. Trichomes of micropropagated plantlets were identical to those of field-growing plants, and essential oil production was observed at early stages of development.The present study confirms that micropropagation under controlled conditions could be an interesting alternative for field production of L. multifida, since higher amounts of plants can be obtained in less time with guarantee of genetic stability and phytossanitary quality, very important features regarding essential oil production and commercialization.

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“…1 The trans-Himalayan cold desert region of India is a repository for an abundance of medicinal plants. 2 Medicinal value of these plants can have a direct benefit for human health and can be helpful in promoting various therapeutic formulations.…”

Section: Introductionmentioning

confidence: 99%

High Efficiency in vitro Plant Regeneration and Secondary Metabolite Quantification from Leaf Explants of Rhodiola imbricata

Bhardwaj¹,

Naryal²,

Bhardwaj³

et al. 2018

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4This stress condition helps in increasing secondary metabolite production. 5 These plants have been used for medico-religious purposes which in turn help in generating income for local people.6 Out of several medicinal plants found in trans-Himalayas, Rhodiola imbricata frames to be a distinctive herb due to the presence of various phytopharmaceutical constituents which can be helpful for human kind. High Efficiency in vitro Plant Regeneration and Secondary Metabolite Quantification from Leaf Explants of Rhodiola imbricataABSTRACT Aim: Rhodiola imbricata is an endangered medicinal plant of the trans-Himalayan Leh-Ladakh region belonging to the family Crassulaceae. An efficient propagation and regeneration system via direct shoot organogenesis from leaf explant and evaluation of cinnamyl alcohol (Secondary metabolite) was established in this study. Material and Methods: In vitro grown leaves were inoculated using Murashige and Skoog (MS) medium supplemented with (alpha)-naphtalene acetic acid (NAA) in combination with 6-benzyladenine (BAP) for callus proliferation and regeneration. Results: The highest percentage of rhizogenous callus was induced in medium containing NAA (10.0-15.0 µM). The highest percentage of shoot formation from leaf derived callus was obtained in the medium containing of NAA (5.0 µM) and BAP (2.5 µM) as well as in NAA (1.0 µM), BAP (5.0 µM) (38.88% and 37.49%) respectively. Rooting of regenerated shoots were effective when a lower concentration of NAA (0.5 μM) was used alone. A maximum number of roots (22.0) and higher length (0.6 cm) was observed. The in-vitro plantlets with well-developed shoots and roots were acclimatized successfully to natural field conditions with a survival rate of over 80%. Cinnamyl alcohol (Secondary metabolite) evaluation was also done for the very first time and an upregulation of 49.6% and 30.6% were observed in in-vitro roots and shoots when compared with mother root and shoot respectively. Hence, it was proved that the content of secondary metabolites obtained from in-vitro raised plants is higher than mother plant. Conclusion : These results may lay a foundation for genetic improvement and can be used to determine sequential level of targeted secondary metabolites through cell culture in Rhodiola imbricata.

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Developing the medicinal plants sector in northern India: challenges and opportunities

Cited by 336 publications

References 29 publications

Sustainable drugs and global health care

Sustainable drugs and global health care

A Rapid and Efficient Protocol for Clonal Propagation of Phenolic-Rich Lavandula multifida

High Efficiency in vitro Plant Regeneration and Secondary Metabolite Quantification from Leaf Explants of Rhodiola imbricata

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