Development and application of three-dimensional light distribution model for laser irradiated tissue

Yoon, Gilwon; Welch, Ashley J.; Motamedi, Massoud; Gemert, Mjc van

doi:10.1109/jqe.1987.1073224

Cited by 132 publications

(50 citation statements)

References 20 publications

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“…For example, this may be due to interaction with structures such as cell membranes, collagen fibrils or cell nuclei [7]. The angular distribution of scattering may be modeled with a Henyey-Greenstein function, parameterized by an anisotropy factor g [8]. Let θ be the deviation in angle of light after a scattering event.…”

Section: Optical Properties Of Tissuementioning

confidence: 99%

Mapping Tissue Optical Attenuation to Identify Cancer Using Optical Coherence Tomography

McLaughlin¹,

Scolaro²,

Robbins

et al. 2009

Medical Image Computing and Computer-Assisted Intervention – MICCAI 2009

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Abstract.The lymphatic system is a common route for the spread of cancer and the identification of lymph node metastases is a key task during cancer surgery. This paper demonstrates the use of optical coherence tomography to construct parametric images of lymph nodes. It describes a method to automatically estimate the optical attenuation coefficient of tissue. By mapping the optical attenuation coefficient at each location in the scan, it is possible to construct a parametric image indicating variations in tissue type. The algorithm is applied to ex vivo samples of human axillary lymph nodes and validated against a histological gold standard. Results are shown illustrating the variation in optical properties between cancerous and healthy tissue.

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Section: Optical Properties Of Tissuementioning

confidence: 99%

Mapping Tissue Optical Attenuation to Identify Cancer Using Optical Coherence Tomography

McLaughlin¹,

Scolaro²,

Robbins

et al. 2009

Medical Image Computing and Computer-Assisted Intervention – MICCAI 2009

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“…The nature and extent of photothermal effects of laser-tissue interactions are governed by (1) the distribution of light within the tissues, (2) tissue temperature, (3) time at temperature and (4) the tissue thermal properties, heat capacity and diffusivity (Welch, 1984;Jacques and Prahl, 1987;Kiejzer et al, 1989;Yoon et al, 1987;Rastegar et al, 1989Motamedi et al, 1989. Distribution of light depends on wavelength and beam diameter, the indices of refraction of the tissue and surrounding media and the scattering and absorption properties of the tissue.…”

Section: Laser and Tissue Parameters: General Considerationsmentioning

confidence: 99%

Pathologic Analysis of Photothermal and Photomechanical Effects of Laser–tissue Interactions

Thomsen

1991

Photochem & Photobiology

533

312

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Abstract-Pathologic analysis of the biologic effects and mechanisms of laser-tissue interactions requires correlation of the irradiation parameters with the biologic status and response of the target tissues over time. The photobiologic mechanisms of laser-induced tissue injury can be separated into three categories, photochemical, photothermal and photomechanical. Anatomic pathologic analysis of laser-induced lesions reveals alterations that represent either specific markers of the photobiologic mechanism or non-specific reactions to tissue injury. Repair, regeneration and wound healing of laser induced lesions appear to be non-specific responses to the type of tissue damage rather than the photobiologic mechanism producing the lesion.

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“…Equal scattering and absorption domain is where both absorption and scattering are substantial, and light in the skin has a strongly collimated component surrounded by a region where light is multiply scattered. This is true for wavelengths between 450 and 590 nm, which include the argon laser and Nd:YAG laser wavelengths, the penetration depth is approximately 0.5 to 2.5 mm [22].…”

Section: Theoretical Backgroundmentioning

confidence: 91%

Photothermal Radiometry for Skin Research

Xiao

2016

Cosmetics

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Photothermal radiometry is an infrared remote sensing technique that has been used for skin and skin appendages research, in the areas of skin hydration, hydration gradient, skin hydration depth profiling, skin thickness measurements, skin pigmentation measurements, effect of topically applied substances, transdermal drug delivery, moisture content of bio-materials, membrane permeation, and nail and hair measurements. Compared with other technologies, photothermal radiometry has the advantages of non-contact, non-destructive, quick to make a measurement (a few seconds), and being spectroscopic in nature. It is also colour blind, and can work on any arbitrary sample surfaces. It has a unique depth profiling capability on a sample surface (typically the top 20 µm), which makes it particularly suitable for skin measurements. In this paper, we present a review of the photothermal radiometry work carried out in our research group. We will first introduce the theoretical background, then illustrate its applications with experimental results.

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Development and application of three-dimensional light distribution model for laser irradiated tissue

Cited by 132 publications

References 20 publications

Mapping Tissue Optical Attenuation to Identify Cancer Using Optical Coherence Tomography

Mapping Tissue Optical Attenuation to Identify Cancer Using Optical Coherence Tomography

Pathologic Analysis of Photothermal and Photomechanical Effects of Laser–tissue Interactions

Photothermal Radiometry for Skin Research

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