Surface water quality at Abuakwa South Municipal has received threats from surrounding mining communities, which are becoming a major concern to the public. As a result, this study aimed to assess water quality by examining the concentration of lead (Pb), cadmium (Cd), and zinc (Zn) pollution in surface water. Fifteen samples were obtained from surface water using a 1.5 L plastic bottle. The mean concentrations of Pb and Cd were above WHO guidelines of 0.01 and 0.003 mg/l, respectively, except for Zn which was below the stipulated limit of 3.0 mg/l. The geochemical process model shows that Cd, Pb, and Zn are adsorbing (released from the drainage to the surrounding environment) in sites 1 and 3 whereas Pb is desorbing (added to the drainage) in site 2. A hazard quotient greater than 1 was recorded for Cd in adults through the ingestion route of exposure at all the sites. Cancer risk also shows that the inhabitants are at risk through the ingestion route of exposure. The findings of this study suggest intake of water draining within the vicinity is unsafe and poses severe health risks.