Development and Characterisation of Chitosan/Pva Nano Fiber for Hemorrhage Control Dressing

Abstract

A wound is a type of physical trauma where in the skin is torn, cut or punctured. Wound may be broadly classified in to open wounds and closed wounds. Incisions or incised wounds, irregular tear-like wounds, superficial wounds, Puncture wounds and penetration wounds falls under the open wound category. Bruises, blood tumor, crush injury, Chronic and acute or traumatic wounds are some of the few examples for closed wounds. In this research work chitosan and PVA with different concentration were used to produce nano fibre film using electro spinning process. The effectiveness of the nano fibre coated with chitosan was analyzed by using SEM, FTIR, antibacterial test, in vitro drug release test and tissue responses in chick nanofilm membrane (CNM) test. The result confirms that the chitosan/PVA nano fibre electro spun film can be effectively used for hemorrhage control dressing.