2018
DOI: 10.31069/japsr.v1i01.13057
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Development and Characterization of Mucoadhesive Buccal Patch of Timolol Maleate

Abstract: Introduction:The oral transmucosal Timolol maleate delivery bypasses liver and avoids presystemic elimination in the gastro intestinal tract and liver which enhance the bioavailability as well decreases the adverse effect. Objective: The present investigation highlights the formulation and evaluation of mucoadhesive buccal patch of Timolol maleate because Timolol maleate has biphasic solubility hence relatively permeated through buccal mucosa, which is well supplied with both vascular and lymphatic drainage. M… Show more

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