2023
DOI: 10.5530/ijpi.14.1.30
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Development and Characterization of Rivastigmine Hydrogen Tartrate Elementary Osmotic Tablets

Ayesha Naz,
Subrahmanyam CVS Subrahmanyam,
Shyam Sunder Rachamalla

Abstract: Background: The present study aims to develop an Elementary Osmotic tablet (EOP) of Rivastigmine Hydrogen Tartrate (RHT). EOP consists of a core tablet suitably coated with a polymeric solution, and an orifice drilled on one side of the tablet. Materials and Methods: The influence of core variables, including sodium chloride (osmogen) concentration and Polyvinyl Pyrrolidine K30 (PVP K30) concentration, have been investigated and optimized by factorial design. The effect of membrane (coating) variables, includi… Show more

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