Development and degradation behavior of magnesium scaffolds coated with polycaprolactone for bone tissue engineering

Yazdimamaghani, Mostafa; Razavi, Mehdi; Vashaee, Daryoosh; Tayebi, Lobat

doi:10.1016/j.matlet.2014.06.036

Cited by 94 publications

(53 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…11 The foremost drawback reported for magnesium alloys has been related to their high corrosion rate in the physiological environment. 12,13 For that reason, an initially low or ideally a controllable absorbable rate is wanted to avoid further deterioration of the adjacent tissue. 14,15 If the magnesium implants are being used to fix damage bone tissue, they are likely to lose their mechanical integrity earlier than tissue healing of bone due to their rapid corrosion and low bioactivity.…”

Section: Materials Science and Engineering: C Vol 48 (March 2015)mentioning

confidence: 99%

In vivo assessments of bioabsorbable AZ91 magnesium implants coated with nanostructured fluoridated hydroxyapatite by MAO/EPD technique for biomedical applications

Razavi

Fathi

Savabi

et al. 2015

Materials Science and Engineering: C

Self Cite

100

View full text Add to dashboard Cite

Although magnesium (Mg) is a unique biodegradable metal which possesses mechanical property similar to that of the natural bone and can be an attractive material to be used as orthopedic implants, its quick corrosion rate restricts its actual clinical applications. To control its rapid degradation, we have modified the surface of magnesium implant using fluoridated hydroxyapatite (FHA: Ca10(PO4)6OH2 − xFx) through the combined micro-arc oxidation (MAO) and electrophoretic deposition (EPD) techniques, which was NOT THE PUBLISHED VERSION; this is the author's final, peer-reviewed manuscript. The published version may be accessed by following the link in the citation at the bottom of the page. 2015): pg. 21-27. DOI. This article is © Elsevier and permission has been granted for this version to appear in e-Publications@Marquette. Elsevier does not grant permission for this article to be further copied/distributed or hosted elsewhere without the express permission from Elsevier. Materials Science and Engineering: C, Vol 48 (March3 presented in our previous paper. In this article, the biocompatibility examinations were conducted on the coated AZ91 magnesium alloy by implanting it into the greater trochanter area of rabbits. The results of the in vivo animal test revealed a significant enhancement in the biocompatibility of FHA/MAO coated implant compared to the uncoated one. By applying the FHA/MAO coating on the AZ91 implant, the amount of weight loss and magnesium ion release in blood plasma decreased. According to the histological results, the formation of the new bone increased and the inflammation decreased around the implant. In addition, the implantation of the uncoated AZ91 alloy accompanied by the release of hydrogen gas around the implant; this release was suppressed by applying the coated implant. Our study exemplifies that the surface coating of magnesium implant using a bioactive ceramic such as fluoridated hydroxyapatite may improve the biocompatibility of the implant to make it suitable as a commercialized biomedical product.

show abstract

Section: Materials Science and Engineering: C Vol 48 (March 2015)mentioning

confidence: 99%

In vivo assessments of bioabsorbable AZ91 magnesium implants coated with nanostructured fluoridated hydroxyapatite by MAO/EPD technique for biomedical applications

Razavi

Fathi

Savabi

et al. 2015

Materials Science and Engineering: C

Self Cite

100

View full text Add to dashboard Cite

show abstract

“…This has led researchers to study porous metals, based on orthopaedic metallic implants, due to their greater compressive strength, fracture toughness, and fatigue resistance, which are needed for load-bearing applications [6,16]. Due to the excellent physical and mechanical properties of magnesium compared to other permanent (nondegradable) metals, porous magnesium and Mg alloys became a good candidate to serve as a biodegradable scaffold for bone treatments [23,24].…”

mentioning

confidence: 99%

Porous magnesium-based scaffolds for tissue engineering

Yazdimamaghani

Razavi

Vashaee

et al. 2017

Materials Science and Engineering: C

Self Cite

241

115

View full text Add to dashboard Cite

“…Mg with Ca, Zn and Mn alloys can be used, to reduce the rate of in vivo corrosion and prevent necrosis and the blocking of blood flow. A human organism well tolerates these alloys [362,363] mainly with coatings adapted to bioresorbable implants [364][365][366][367]. Reinforcements of magnesium MMCs usually include, notably, HA [368][369][370][371][372][373], FA [374], calcium polyphosphate [375], and calcium [374] and well affect biocompatibility.…”

Section: Selection Of Materials Of Implantable Devices In Regenerativmentioning

confidence: 99%

Introductory Chapter: Multi-Aspect Bibliographic Analysis of the Synergy of Technical, Biological and Medical Sciences Concerning Materials and Technologies Used for Medical and Dental Implantable Devices

Dobrzański¹

2018

Biomaterials in Regenerative Medicine

View full text Add to dashboard Cite

Development and degradation behavior of magnesium scaffolds coated with polycaprolactone for bone tissue engineering

Cited by 94 publications

References 30 publications

In vivo assessments of bioabsorbable AZ91 magnesium implants coated with nanostructured fluoridated hydroxyapatite by MAO/EPD technique for biomedical applications

In vivo assessments of bioabsorbable AZ91 magnesium implants coated with nanostructured fluoridated hydroxyapatite by MAO/EPD technique for biomedical applications

Porous magnesium-based scaffolds for tissue engineering

Introductory Chapter: Multi-Aspect Bibliographic Analysis of the Synergy of Technical, Biological and Medical Sciences Concerning Materials and Technologies Used for Medical and Dental Implantable Devices

Contact Info

Product

Resources

About