Development and evaluation of an integrated pharmaceutical education system

Bioequivalence of Generic Drugs Commercialised on the Canadian Market

“…Similar to previous studies that demonstrated deficiencies in the generic drug market in other countries [7][8][9], we have also highlighted several deficiencies in the Canadian generic drug market. The deficiencies found in those studies are similar to ours and they can fit in one of the following categories: unpublished monographs, non-respect of Health Canada's guidelines and non-bioequivalence.…”

“…Studies done in the United-States of America [7,8] and in Europe [9] investigated independently whether generic drugs released were bioequivalent to their brand-name counterparts. These studies revealed a fair amount of irregularities, which consisted mostly of 1-non-respect of the governing authority's guidelines (such as incomplete reports, dissolution methods used, bioanalytical methodology); 2-missing elements in the drug reports (such as missing operation procedure, missing storage information, missing analytical data, missing administration method) and 3-pharmacokinetic parameters not meeting bioequivalency requirements (C max and AUC ∞ test/reference ratio exceeding the 90% CI are not considered bioequivalent).…”

“…The work from Van Der Meersch et al [9] relies on published data that was used to obtain commercialisation authorization, while the work presented by Davit et al [7] and Liu et al [8] refers to information contained in monographs appearing on websites of government organisations once the generic has been approved for commercialisation. Thus, the data by Van Der Meersch et al [9] could include some errors that should be eventually detected by each country's regulatory agencies and may prohibit market access authorisation.…”

ICT-based health information services for elderly people: Past experiences, current trends, and future strategies

“…genetic diseases [21,22], prostate cancer [23], asthma [24], or diabetes [25], some of which have a high prevalence in-though are not exclusive to-elderly people. Liu et al present a pharmaceutical education system for patients that accounts for the patient's individual informational needs by making use of personal information taken from a hospital information system and by tailoring the information given to the patient accordingly [26].…”