Objectives: This study aimed to examine the association between psychiatric nurses’ empathy, teamwork, nursing work environment, and the degree of person-centered care, as well as to identify factors influencing person-centered care (PCC). Methods: An online cross-sectional survey was conducted from 11 January to 19 January 2024, using four validated questionnaires. Results: Participants included 167 psychiatric nurses with more than one year of clinical experience working in South Korea. Person-centered care was positively correlated (p < 0.001) with empathy, teamwork, and the nursing work environment. Hierarchical regression analysis was used to identify factors influencing person-centered care among psychiatric nurses. The analysis revealed that the nursing work environment (p < 0.001), teamwork (p < 0.001), empathy (p < 0.001), type of hospital (general hospital) (p = 0.002), and age (p = 0.037) significantly influenced person-centered care, explaining 78.7%. Conclusions: Enhancing PCC among psychiatric nurses requires the development of training and educational programs that bolster empathy and teamwork. Additionally, improvements and strategic enhancements to the nursing work environment are essential.