Development and Evaluation of Polyherbal Lozenges for Cold and Flu

Kumar, A. S. Kiran; Mishra, Manish; Afeefa,; Chandrashekar, K. S.; Pai, Girish K; Pai, Vasudev

doi:10.5530/ijper.53.2s.61

Cited by 6 publications

(6 citation statements)

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“…did not follow a similar trend since a gum base was not employed (Kumar et al, 2019). The previous studies clearly explain neem gum's influence on the formulated lozenge.…”

Section: Physical Parametersmentioning

confidence: 78%

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Formulation and evaluation of medicated lozenges using traditional herbs to treat sore throat infection

Kadirvel¹,

Mithulesh²,

Narayana³

et al. 2022

Food Processing Preservation

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tween 5 to 16 years are caused by viruses (Worrall, 2011). Recently, the sore, prickly, itchy, and swollen throat has become the most prevalent symptom of COVID-19 infection (WHO, 2020). The treatment of various medical conditions, including sore throat, is done via oral drug delivery as they accurately monitor the dosage, enable self-medication, better patient conformity, and avert pain. However, the solid dosage forms cannot be consumed by the patients having dysphagia, which causes difficulty in swallowing. Lozenges are designed with drugs incorporated for dysphagia patients and require the slow release of drugs in the mouth. The consumption of medicated lozenges is considered the universal remedy for a sore throat. Medicated lozenges are flavored hard candies containing one or more active ingredients intended to be sucked and held in the mouth to reduce the pain and soothe the tissues of the throat

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“…did not follow a similar trend since a gum base was not employed (Kumar et al, 2019). The previous studies clearly explain neem gum's influence on the formulated lozenge.…”

Section: Physical Parametersmentioning

confidence: 78%

“…The thickness of the medicated lozenge diminishes with the reduction in the concentration of neem gum. However, the lozenge formulated by Kumar et al did not follow a similar trend since a gum base was not employed (Kumar et al, 2019). The previous studies clearly explain neem gum's influence on the formulated lozenge.…”

Section: Resultsmentioning

confidence: 99%

Formulation and evaluation of medicated lozenges using traditional herbs to treat sore throat infection

Kadirvel¹,

Mithulesh²,

Narayana³

et al. 2022

Food Processing Preservation

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show abstract

“…Organoleptic characterization of the prepared lozenges was carried out to evaluate their properties such as taste, odor, color, softness, surface smoothness, and shape [33].…”

Section: Organoleptic Propertiesmentioning

confidence: 99%

Natural ingredients included antimicrobial lozenge formulations for oral care

ESENTÜRK GÜZEL,

ABDO,

TOPUZOĞLU

et al. 2024

jrp

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Lozenges are easy-to-use solid/semi-solid dosage forms that can contain one or more active ingredients, which can be used in the local treatment of mouth and throat infections. Honey, propolis, and perga, which are bee hive natural products have properties of antimicrobial and nutrient. While the oil of seaweed has a rich omega-3 content, the essential oils of pine turpentine, juniper, eucalyptus, sage, lemon balm, and tea tree have antimicrobial properties. In this study, it is aimed to prepare the above indicated ingredients included antimicrobial lozenges. Prepared formulations were evaluated by characterization and antimicrobial efficiency tests. Characterization tests included the determination of organoleptic parameters, weight variation, friability, and in vitro disintegration time. Antimicrobial efficacy was determined with the antimicrobial activities of lozenges against group A β-hemolytic streptococci, group B β-hemolytic streptococci, Staphylococcus aureus, Klebsiella pneumoniae, and Candida albicans which was evaluated by broth microdilution and time-kill studies. Results showed that all the formulations showed acceptable characterization profiles and antimicrobial efficiency. The lozenge formulation, which included honey, propolis, Perga, seaweed oil, and essential oils of pine turpentine, juniper, and eucalyptus can be accepted as the best formulation in terms of antimicrobial activities against all of the tested microorganisms especially Group A beta-hemolytic streptococci which is the most frequent bacterial pathogen causing sore throat in the oral cavity. In conclusion, natural ingredients included lozenges can be a good alternative for oral care products with their good antimicrobial properties for a wide range of populations.

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“…As a control, a regular gentamicin solution was employed [16,17]. The zone of inhibition is then evaluated after it has been incubated for 24 hours at 37 • C [18][19][20].…”

Section: Time For Dissolutionmentioning

confidence: 99%

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2023

Fut J. Pharm & H. Sci

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Development and Evaluation of Polyherbal Lozenges for Cold and Flu

Cited by 6 publications

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Formulation and evaluation of medicated lozenges using traditional herbs to treat sore throat infection

Formulation and evaluation of medicated lozenges using traditional herbs to treat sore throat infection

Natural ingredients included antimicrobial lozenge formulations for oral care

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