Development and evaluation of TWIST Dixon for dynamic contrast‐enhanced (DCE) MRI with improved acquisition efficiency and fat suppression

Le, Yuan; Kroeker, Randall; Kipfer, Hal D.; Lin, Chen

doi:10.1002/jmri.23663

Cited by 51 publications

(30 citation statements)

References 34 publications

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“…Magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS) provides the highest precision (sensitivity and specificity) in quantifying steatosis and liver fat mapping (26). Based on promising emerging data, MRI and MRS may become the gold standard for the diagnosis and management of NAFLD in the near future, although they are currently limited bv cost and availability (27,28).…”

Section: Diagnosis: Abdominal Imagingmentioning

confidence: 99%

Nonalcoholic Fatty Liver Disease Review: Diagnosis, Treatment, and Outcomes

Ahmed

Wong

Harrison

2015

Clinical Gastroenterology and Hepatology

286

202

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Nonalcoholic fatty liver disease (NAFLD) is the most common cause of abnormal serum aminotransferase levels in both developed and developing countries. Patients with nonalcoholic steatohepatitis (NASH), a subset of NAFLD, are at risk for progressive liver disease and in need of effective treatment options. A practical approach may be pursued by identifying patients with NAFLD with the highest likelihood for histologic evidence of NASH. Despite decades of clinical trials, no single treatment can be recommended to all patients with NASH. Importantly, there is no evidence that pioglitazone or vitamin E improves fibrosis. Bariatric surgeries may improve hepatic histology in morbidly obese patients with NASH, although randomized clinical trials are lacking. Currently, NASH is the second leading etiology of liver disease among adults awaiting liver transplantation in the United States. The primary and secondary prevention of NAFLD may require aggressive strategies for managing obesity, diabetes, and metabolic syndrome.

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Section: Diagnosis: Abdominal Imagingmentioning

confidence: 99%

Nonalcoholic Fatty Liver Disease Review: Diagnosis, Treatment, and Outcomes

Ahmed

Wong

Harrison

2015

Clinical Gastroenterology and Hepatology

286

202

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“…Time-resolved angiography with interleaved stochastic trajectories (TWIST) or time-resolved imaging of contrast kinetics (TRICS) MR angiography is a technique which provides high temporal resolution images during the arterial, capillary and venous phases [27]. This technique is a reliable tool for the evaluation of the feeding arteries, the nidus and draining veins of arteriovenous malformations of the head & neck [28,29].…”

Section: Vessels and Perfusion: 3d-tof Twist/tricks Angiography Dcementioning

confidence: 99%

MRI Sequences in Head & Neck Radiology – State of the Art

Widmann¹,

Henninger²,

Kremser³

et al. 2017

Fortschr Röntgenstr

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ZUSAMMENFASSUNGHintergrund Magnetic resonance imaging (MRI) ist ein essentielles bildgebendes Verfahren für die Beurteilung von Kopf-Hals Erkrankungen. Die diagnostische Aussagekraft der MRI ist jedoch stark von der entsprechenden Auswahl und Interpretation der Protokolle und Sequenzen abhängig. Das Ziel dieses Beitrags ist es, State-of-the-art-Sequenzen für die klinische Routine der Kopf-Hals-MRI zusammenzufassen und die Evidenz zu beschreiben, für welche medizinische Fragestellungen diese Sequenzen nützlich sind.Methode Literaturübersicht von State-of-the-art-Sequences in der Kopf-Hals-MRI.

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“…A spline and body matrix coil was used. A similar 3D T1-weighted gradient echo sequence with a dual-echo bipolar readout was used for data acquisition (a TWIST-Dixon work-in-progress sequence 14 ) to achieve high spatiotemporal resolution, and the same two-point Dixon reconstruction was used for robust fat-water separation. No parallel imaging was used in this acquisition.…”

Section: A2 Noncontrast Mr Image Acquisition Under Free Breathingmentioning

confidence: 99%

Shape‐based motion correction in dynamic contrast‐enhanced MRI for quantitative assessment of renal function

2014

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Purpose: To incorporate a newly developed shape-based motion estimation scheme into magnetic resonance urography (MRU) and verify its efficacy in facilitating quantitative functional analysis. Methods: The authors propose a motion compensation scheme in MRU that consists of three sequential modules: MRU image acquisition, motion compensation, and quantitative functional analysis. They designed two sets of complementary experiments to evaluate the performance of the proposed method. In the first experiment, dynamic contrast enhanced (DCE) MR images were acquired from three sedated subjects, from which clinically valid estimates were derived and served as the "ground truth." Physiologically sound motion was then simulated to synthesize image sequences influenced by respiratory motion. Quantitative assessment and comparison were performed on functional estimates of Patlak number, glomerular filtration rate, and Patlak differential renal function without and with motion compensation against the ground truth. In the second experiment, the authors acquired a temporal series of noncontrast MR images under free breathing from a healthy adult subject. The performance of the proposed method on compensating real motion was evaluated by comparing the standard deviation of the obtained temporal intensity curves before and after motion compensation. Results: On DCE-MR images with simulated motion, the generated relative enhancement curves exhibited large perturbations and the Patlak numbers of the left and right kidney were significantly underestimated up to 35% and 34%, respectively, compared with the ground truth. After motion compensation, the relative enhancement curves exhibited much less perturbations and Patlak estimation errors reduced within 3% and 4% for the left and right kidneys, respectively. On clinical free-breathing MR images, the temporal intensity curves exhibited significantly reduced variations after motion compensation, with standard deviation decreased from 30.3 and 38.2 to 8.3 and 11.7 within two manually selected regions of interest, respectively.

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Development and evaluation of TWIST Dixon for dynamic contrast‐enhanced (DCE) MRI with improved acquisition efficiency and fat suppression

Cited by 51 publications

References 34 publications

Nonalcoholic Fatty Liver Disease Review: Diagnosis, Treatment, and Outcomes

Nonalcoholic Fatty Liver Disease Review: Diagnosis, Treatment, and Outcomes

MRI Sequences in Head & Neck Radiology – State of the Art

Shape‐based motion correction in dynamic contrast‐enhanced MRI for quantitative assessment of renal function

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