2020
DOI: 10.1016/j.jddst.2020.101714
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Development and evaluation of zopiclone compression coated tablet for time-controlled pulse release: Mechanism and in vivo study

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Cited by 4 publications
(2 citation statements)
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“…For screening, 0.5 g of the lipid was melted at 80 °C, and then, in 1 mL of acetone, 10 mg of ZP was dissolved and added to the lipid. The vials were kept on a hot plate magnetic stirrer at 80 °C for 1 h, then the amount of ZP was determined spectrophotometrically (UV-1601 PC; Shimadzu, Kyoto, Japan)at λ max = 304 nm ( Zhou et al, 2020 ) after 10-folds dilution with methanol. The lipid with the maximum drug solubility was chosen for further preparation of NLCs.…”
Section: Methodsmentioning
confidence: 99%
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“…For screening, 0.5 g of the lipid was melted at 80 °C, and then, in 1 mL of acetone, 10 mg of ZP was dissolved and added to the lipid. The vials were kept on a hot plate magnetic stirrer at 80 °C for 1 h, then the amount of ZP was determined spectrophotometrically (UV-1601 PC; Shimadzu, Kyoto, Japan)at λ max = 304 nm ( Zhou et al, 2020 ) after 10-folds dilution with methanol. The lipid with the maximum drug solubility was chosen for further preparation of NLCs.…”
Section: Methodsmentioning
confidence: 99%
“…The prepared NLCs were then dissolved in methanol ( Al-Attas et al, 2017 ) by sonication for 5 min. Entrapped ZP amount was then determined spectrophotometrically at λ max = 304 nm ( Zhou et al, 2020 ) by using an appropriate calibration curve of pure ZP in methanol, EE% is calculated as follows, Eq. 1: 100 …”
Section: Methodsmentioning
confidence: 99%