Development and in vitro characterization of sol–gel derived CaO–P2O5–SiO2–ZnO bioglass

Magnetron Sputtered BG Thin Films: An Alternative Biofunctionalization Approach – Peculiarities of Bioglass Sputtering and Bioactivity Behaviour

“…Glasses of the Na 2 O-CaO-P 2 O 5 -SiO 2 system can be either formed from the traditional melt-quenching (Wu et al, 2011) or by the modern sol-gel method (Balamurugan et al, 2007). It has also been proved that an increase in the growth rate of apatite-like layer as well as the wider bioactivity were observed depending on the compositional range used for the preparation of bioglass (Rámila & Vallet-Regí, 2001;Vallet-Regí et al, 2003).…”

In vitro evaluation of bioactivity of SiO2-CaO-P2O5-Na2O-CaF2-ZnO glass-ceramics

“…The variation of pH of SBF solutions is consistent with the mechanism of nucleation proposed by Hench et al [22] and the growth of bone-like apatite layer on the surface of bioactive materials, but at the very initial stage a slight decrease in pH of solution was also observed for all glass-ceramic samples except the BZn0. This decrease can be understood by taking into account the initial fast release of zinc ions to SBF solution, which changes the solution acidity [2,23]. It was also found that the enhanced release of zinc ions causes simultaneous decrease of both pH of the solution and amount of Si ions leached out from the sample as ZnO has been known as an amphoteric oxide that improves chemical durability by reducing the dissolution rate of glass-ceramic samples by decreasing the number of non-bridging oxygens [3,11].…”

“…Glass-ceramics have been widely used as bone grafts or fillers for orthopaedic and dental applications. The most useful property of glass-ceramics, which shows the ability of the material to form a direct bond to a living bone, is bioactivity [2]. Bioactivity is a spontaneous communication of materials in biological environment, which results in strong adhesion between tissue-implant interface [3].…”

“…Zinc is an essential trace element [2,[4][5][6][7] whose addition promotes bone formation as it stimulates osteoblast proliferation and differentiation [8]. In addition to that it has profound antibacterial properties [9,10].…”

Bioactive Microarc Oxidized TiO2-based Coatings for Biomedical Implication

“…Thus, to prepare bioactive coatings on titanium and its alloys is an approach to resolving the disadvantages of ceramic and metal biomaterials. Many surface modifying techniques (e.g., plasma spraying (Zheng et al, 2000), sol-gel method (Wen et al, 2007;Balamurugan et al, 2007), biomimetic and electrochemical deposition (Zhang et al, 2005)) have been developed to deposit bioactive coating on titanium and its alloys. Microarc oxidation (MAO) is a relatively convenient and effective technique to deposit bioceramic coatings on the surfaces of Ti and its alloys (Yerokhin et al, 1999).…”