Development and mechanical characterization of porous titanium bone substitutes

Abstract

is an open access repository that collects the work of Arts et Métiers ParisTech researchers and makes it freely available over the web where possible. Commercially Pure Porous Titanium (CPPTi) can be used for surgical implants to avoid the stress shielding effect due to the mismatch between the mechanica l properties of titanium and bone . Most researchers in this area deal with randomly distributed pores or simple architectures in titanium alloys. The control of porosity, pore size and distribution is necessary to obtain implants with mechanical properties close to those of bone and to ensure their osseointegration . The aim of the present work was therefore to develop and characterize such a specific porous structure. First of all, the properties of titanium made by Selective Laser Melting (SLM) were characterized through experimental testing on bulk specimens. An elementary pattern of the porous structure was then designed to mimic the orthotropic properties of the human bone following several mechanical and geometrical criteria . Finite Element Analysis (FEA) was used to optimize the pattern . A porosity of 53% and pore sizes in the range of 860 to 1500 µm were fi.nally adopted . Tensile tests on porous samples were then carried out to validate the properties obtained numerically and identify the failure modes of the sam_ples. Final!y, FE elasto_plastic ana!yses were yerformed on the porous samples in order to propose a failure criterion for the design of porous substitutes . .

Mechanical behavior of porous commercially pure Ti and Ti–TiB composite materials manufactured by selective laser melting

“…This has directed to the development of Ti-based materials having Young's modulus closer to that of bone, including designing and producing new Ti alloys with lower stiffness [3][4][5][6]. Another solution is to use a porous metallic structure instead of bulk fully-dense materials [7,8]. Porous Ti-based parts have lower weight in comparison with fully-dense Ti implants and are considered for joint replacement surgery and bone grafting because porous structures not only have mechanical properties close to that of human bone but also allows bone in-growth which leads to stable long-term fixation of implants [9,10].…”

Osteostatin-Coated Porous Titanium Can Improve Early Bone Regeneration of Cortical Bone Defects in Rats

“…22 A recently explored peptide that has potential to equip titanium with osteoinductive properties is osteostatin. Osteostatin is the N-terminal sequence 107-111 of the C-terminal domain of parathyroid hormone (PTH)-related protein (PTHrP).…”

Guías y miniplacas personalizadas: un protocolo guiado para cirugía ortognática

“…Sabemos que un implante demasiado rígido puede producir un estrés local secundario, que contribuya a medio-largo plazo a una osteopenia, al contrarrestarse los estímulos necesarios para un correcto remodelado óseo 24,25 . No obstante, cuando ese implante se va a utilizar como medio de transferencia de información para posicionar un fragmento osteotomizado, este debería ser rígido, o con una capacidad de recuperación elástica a la deformación elevada, para no introducir errores durante la cirugía.…”