Hollow self-inducing impellers are often used in gas-liquid stirred tanks in many industrial processes. To understand the hydrodynamics characteristics of this type of stirred tank under aerated and unaerated conditions, a computational fluid dynamics (CFD) simulation study was conducted. The predicted gas self-inducing flow rate, power consumption, and impeller power number were compared with the experimental data in the literature and discussed. Under unaerated conditions, liquid level in the hollow shaft relies on the impeller speed, and is slightly influenced by the impeller clearance. Self-inducing impeller power number remains almost unchanged with impeller speed, while increasing with the rise of the impeller clearance. Under aerated conditions, gas is easy to accumulate in the centre of the upper and lower circulation loops. Gas self-inducing flow rate, global gas holdup, and power consumption increase with higher impeller speed. The critical impeller speed for gas self-induction decreases with higher impeller clearance. At the same impeller speed, gas self-inducing flow rate and global gas holdup increase, while power consumption reduces with increasing of impeller clearance.