Background. Medical simulation as a teaching method is concerned with close mirroring of the real clinical conditions, it is designed to develop skills from the clinical environment, under the guidance of experienced instructors, it allows standardization and repeatability of the skills taught. As a result, students acquire skills and competences, become acquainted with the medical equipment needed to perform a given procedure without endangering patients. The presented research attempts to evaluate the application of medical simulation techniques in the teaching of basic clinical skills using original instructional videos and the Peyton approach. Also, an attempt was made to assess how the applied interventions affect the assessment regarding the usefulness of the course by the students of medicine in comparison with the results of practical assessment in the form of OSCE. Materials. The research was conducted in the period from May 2015 to June 2017, among 750 students of the medical faculty of the Medical University in Lublin. The study used a self-reported questionnaire and documentation analysis with the results of practical assessment. The obtained results were statistically analyzed.Results. The overall students scored the BCS course high (good and very good). The highest values were assigned to Stage III of the research. The introduction of simulation techniques along with the original instructional videos and the Peyton approach positively reflected in the results obtained in the final assessment, OSCE, especially in case of invasive procedures: peripheral vein cannulation and urinary bladder catheterization. Conclusions. Consequently, obtained results allowed concluding that the use of medical simulation techniques in the teaching of basic clinical skills using modern methodologies and teaching interventions: original instructional videos and the Peyton approach affected the positive assessment of the usefulness of the simulation course by students, as well as improve and support the process of acquiring basic skills clinical in the early years of medical training.