This paper describes the evaluation method of the new Japanese thrusters design, balancing and verification of interface compatibility with the HTV system and operation design. Thruster performance directly affects the performance of the space craft. Therefore, the thruster replacement from the imported thrusters to the new Japanese thrusters required the evaluation from the view point of high-order system level. It is important to select the appropriate elements, verify their relationships, and create a feedback mechanism which allows modification of each element. This method will facilitate the overall systems design for future inter-orbit transfer vehicles.