Development and study of modified film coatings with controlled transport properties

Хакамов, Т. Ш.; Feoktistov, Dmitriy; Badykova, L. A.; Корнилаев, П. Г.; Shavaleev, R. R.; Mudarisova, R. Kh.

doi:10.1134/s1070427213090175

Cited by 9 publications

(2 citation statements)

References 2 publications

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“…Previous research has suggested that hydrogels containing a higher concentration of a crosslinker have higher G ′ values, which means that they are mechanically stronger and more elastic 35 . In addition, Khakamov et al suggested that the interaction of pectin and PVA can possibly produce stronger bonds than those in pectin associates, explaining that the formation of these interaction is due to hydrogen bonding and hydrophobic interactions between the macromolecules of pectin and PVA 36 …”

Section: Resultsmentioning

confidence: 99%

Preparation and properties of physically cross‐linked PVA/pectin hydrogels blended at different ratios for wound dressings

Choi

Park

et al. 2021

J of Applied Polymer Sci

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In the present study, we fabricated composite polyvinyl alcohol (PVA) and pectin hydrogels with different blend ratios using a freeze–thaw method. Scanning electron microscopy revealed that the PVA/pectin hydrogels had a porous structure, with the porosity increasing from 82.8% ± 0.5% to 93.2% ± 0.3% with an increase in the pectin content. In addition, with the addition of pectin, the gel fraction of the hydrogel decreased and the swelling ability increased compared with PVA. Of the fabricated hydrogels, the hydrogel with the 9:1 PVA/pectin ratio had the highest compressive strength (684 ± 62 kPa) and G′ value (~1014 kPa). Based on cytotoxicity studies, none of the fabricated hydrogels showed cytotoxicity against HDF or HaCaT cells. These results indicate that varying the pectin content can be used to control the mechanical characterization, porosity, and swelling ability of composite PVA/pectin hydrogels, which are thus promising candidates for use as wound dressings.

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Section: Resultsmentioning

confidence: 99%

Preparation and properties of physically cross‐linked PVA/pectin hydrogels blended at different ratios for wound dressings

Choi

Park

et al. 2021

J of Applied Polymer Sci

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“…[23][24][25][26][27] When modified, in particular, with phosphoric acid, the ability of chitosan to form fibers and films increases, as well as its sorption properties. [24][25][26][27][28] Phosphoric acid, as a strong nucleophile (reagent), can affect the position of OH groups connected with the terminal glycosidic center of the chitosan molecule. Probably, the phosphoric acid anion can form a stable complex with the terminal glycosidic center of chitosan.…”

Section: Introductionmentioning

confidence: 99%

Electrochemical formation of ion-conducting oxo-phosphate-molybdate polymer on aluminium

Hussein

Popova

Frolova

et al. 2021

JSCS

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The state of the electrochemical behavior of the Al electrode in aqueous solutions containing Na2MoO4 + H3PO4 + chitosan was investigated by methods of currentless chronopotentiometry, chronoamperometry, optical and scanning electron microscopy. The modification of the surface polymo-lybdate phosphate layers was carried out in a potentiostatic mode in the potentials range from -1 to -3 V and polarization time (from 15 to 90 min). The elemental composition of the surface layer of the metal before and after cathodic polarization were investigated. The electrochemical formation of matrix polymeric structures from ion-conducting (H+, Na+) heteronuclear poly-molybdate and polyphosphate-molybdate complexes of double salts Na6AlnMo7-nO24 and Na2yAl2(MoO4)y(PO4)3-y was established. The rate of hydrogen and sodium intercalation into the structure of the polyoxophosphate-molybdate layer increased sharply with an increase of the potential range from -1.3 V to -3.0 V. The addition of chitosan into the solution enhances the film-forming effect of surface ion-conducting oxo-phosphate - molybdate polymeric layer.

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Inulin–Niacin Conjugates: Preparation, Characterization, Kinetic and In Vitro Release Studies

et al. 2021

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Niacin, an essential B-complex vitamin, used in the treatment of nonalcoholic fatty liver disease is the rst perceived lipid regulating medication, inhibits and reverses hepatic steatosis and in ammation in animals and liver cell cultures. Niacin shows bene cial effects on adiposity. Niacin plays an important role in DNA repair, electron transfer, one-carbon metabolism and fatty acid synthesis in cells. Natural polysaccharides with desirable chemical modi cations can be combined with vitamins for developing the supplement treatment for vitamin de ciency disorders. Modi cation of inulin was carried out by tosylation, amination and then conjugated with niacin. Structural elucidation of the derivatives and conjugates was carried out by FT-IR, 1 H NMR and SEM. Thermal behavior was investigated by TGA and DSC techniques. The release and kinetics of niacin, from the conjugate, at different pH was studied. The release was observed to be pH dependent, showing a greater release at higher pH following Korsmeyer-Peppas kinetic model. Polysaccharide based approach was used for the preparation of stable niacininulin conjugates with controllable and prolonged release of niacin. These types of conjugates may be useful as vitamin delivery systems for vitamin de ciency disorders.

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Development and study of modified film coatings with controlled transport properties

Cited by 9 publications

References 2 publications

Preparation and properties of physically cross‐linked PVA/pectin hydrogels blended at different ratios for wound dressings

Preparation and properties of physically cross‐linked PVA/pectin hydrogels blended at different ratios for wound dressings

Electrochemical formation of ion-conducting oxo-phosphate-molybdate polymer on aluminium

Inulin–Niacin Conjugates: Preparation, Characterization, Kinetic and In Vitro Release Studies

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