Development and Validation of a Risk Score for Respiratory Failure After Cardiac Surgery

Zainab, Asma; Nguyen, Duc T.; Graviss, Edward A.; Fatima, Sahar; Masud, Faisal; MacGillivray, Thomas E.

doi:10.1016/j.athoracsur.2021.03.082

Cited by 7 publications

(3 citation statements)

References 24 publications

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“…The meta-analysis shows that PMV was significantly associated with the SAVR + CABG surgical operation. Longer CPB time is reported to be an independent predictor of postoperative respiratory failure [ 74 ] and PMV (> 24 h) [ 75 ]. Since SAVR + CABG operation has a CPB time longer than i-SAVR, we can argue that this factor might be determinant in increasing the incidence of postoperative PMV in patients who received CABG added to SAVR.…”

Section: Discussionmentioning

confidence: 99%

The early and long-term outcomes of coronary artery bypass grafting added to aortic valve replacement compared to isolated aortic valve replacement in elderly patients: a systematic review and meta-analysis

et al. 2022

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In aged population, the early and long-term outcomes of coronary revascularization (CABG) added to surgical aortic valve replacement (SAVR) compared to isolated SAVR (i-SAVR) are conflicting. To address this limitation, a meta-analysis comparing the early and late outcomes of SAVR plus CABG with i-SAVR was performed. Electronic databases from January 2000 to November 2021 were screened. Studies reporting early-term and long-term comparison between the two treatments in patients over 75 years were analyzed. The primary endpoints were in-hospital/30-day mortality and overall long-term survival. The pooled odd ratio (OR) and hazard ratio (HR) with 95% confidence interval (CI) were calculated for in-early outcome and long-term survival, respectively. Random-effect model was used in all analyses. Forty-four retrospective observational studies reporting on 74,560 patients (i-SAVR = 36,062; SAVR + CABG = 38,498) were included for comparison. The pooled analysis revealed that i-SAVR was significantly associated with lower rate of early mortality compared to SAVR plus CABG (OR = 0.70, 95% CI 0.66–0.75; p < 0.0001) and with lower incidence of postoperative acute renal failure (OR = 0.65; 95% CI 0.50–0.91; p = 0.02), need for dialysis (OR = 0.65; 95% CI 0.50–0.86; p = 0.002) and prolonged mechanical ventilation (OR = 0.57; 95% CI 0.42–0.77; p < 0.0001). Twenty-two studies reported data of long-term follow-up. No differences were reported between the two groups in long-term survival (HR = 0.95; 95% CI 0.87–1.03; p = 0.23). CABG added to SAVR is associated with worse early outcomes in terms of early mortality, postoperative acute renal failure, and prolonged mechanical ventilation. Long-term survival was comparable between the two treatments.

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Section: Discussionmentioning

confidence: 99%

The early and long-term outcomes of coronary artery bypass grafting added to aortic valve replacement compared to isolated aortic valve replacement in elderly patients: a systematic review and meta-analysis

et al. 2022

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“…Respiratory failure is one of the most common complications after cardiac surgery [1][2][3]. Most patients recover in a short period due to sufficient cardiopulmonary reserve.…”

Section: Introductionmentioning

confidence: 99%

“…However, high-risk patients with existing respiratory diseases or who underwent prolonged cardiopulmonary bypass may experience a postoperative decline in respiratory function. As a result, these patients may eventually suffer extubation failure, resulting in a prolonged intensive care unit (ICU) stay or an increased risk of mortality [3][4][5].…”

Section: Introductionmentioning

confidence: 99%

Remifentanil versus Dexmedetomidine in Cardiac Surgery Patients with Noninvasive Ventilation Intolerance: Protocol for the REDNIVI Trial

Luo¹,

Hao²,

Li³

et al. 2022

Rev. Cardiovasc. Med.

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Background: Respiratory failure is one of the most common complications following cardiac surgery. Although noninvasive ventilation (NIV) has been an effective treatment, it has a high rate of intolerance. Both remifentanil and dexmedetomidine are used as sedatives in cardiac surgery (CS) patients with NIV intolerance. However, no randomized controlled trials have compared the effects of these drugs in relieving the intolerance. Methods: REDNIVI will be a multicenter, prospective, single-blind, randomized controlled trial carried out in six clinical sites in China. Subjects with NIV intolerance will be randomized to receive remifentanil or dexmedetomidine in a ratio of 1:1. Primary outcomes of intolerance remission rate at different timings (15 minutes, 1, 3, 6, 12, 24, 36, 48, 60, 72 hours after initiation of treatment) and 72 h average remission rate will be determined. In addition, secondary outcomes such as mortality, duration of intensive care unit (ICU) stay, duration of mechanical ventilation (MV), the need for endotracheal intubation, hemodynamic changes, and delirium incidence will also be determined. Conclusions: This trial will provide evidence to determine the effects of remifentanil and dexmedetomidine in patients with NIV intolerance after cardiac surgery. Clinical Trial Registration: This study has been registered on ClinicalTrials.gov (NCT04734418).

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Intensivtherapie nach herzchirurgischen Eingriffen

Vogel

Ninke²,

Zwißler³

et al. 2023

Die Intensivmedizin

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Development and Validation of a Risk Score for Respiratory Failure After Cardiac Surgery

Cited by 7 publications

References 24 publications

The early and long-term outcomes of coronary artery bypass grafting added to aortic valve replacement compared to isolated aortic valve replacement in elderly patients: a systematic review and meta-analysis

The early and long-term outcomes of coronary artery bypass grafting added to aortic valve replacement compared to isolated aortic valve replacement in elderly patients: a systematic review and meta-analysis

Remifentanil versus Dexmedetomidine in Cardiac Surgery Patients with Noninvasive Ventilation Intolerance: Protocol for the REDNIVI Trial

Intensivtherapie nach herzchirurgischen Eingriffen

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