“…Some of the reported methods for determination of NPS includes titrimetric , potentiometric (Lenik et al, 2002;Uysal et al,2004),spectrophotometric (Maheshwari et al, 2009 andYola et al, 2011;Kulsum et al,2011;Dharmalingam et al, 2013), mass spectrometric (Pracz et al, 2012), electrophoretic (Macia et al,2008),GC (Singh et al, 1991;), HPLC (Tashtoush et al, 2003;Mehta et al, 2012;Haque et al, 2012;Tanjin et al, 2013) and LC-MS (Elsinghorst et al, 2011) methods. The literature survey indicates there is only a single stability-indicating UPLC method for determination of NPS (Venkatarao et al, 2012).…”