Development and validation of a nomogram incorporating selected systemic inflammation-based prognostic marker for complication prediction after vascularized fibula flap reconstruction

Liu, Zhongqi; Wu, Haixuan; Liufu, Ning; Cheng, Shi Yuan; Huang, Haoquan; Hu, Chuwen; Cao, Minghui

doi:10.1016/j.oraloncology.2019.104467

Cited by 15 publications

(17 citation statements)

References 39 publications

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“…In order to assign scores to three combination of albumin and NLR, we set the rule that the higher ANS value, the higher complication rate. This rule is consistent with previous related studies (22)(23)(24). Therefore, values of albumin below 37.45 g/L were given 1 point.…”

Section: Data Collectionsupporting

confidence: 91%

“…Youden index integrates sensitivity and specificity information under circumstances that emphasize both sensitivity and specificity. The maximum value of the index provides the best tradeoff between sensitivity and specificity, and it can be used as a cut-off for numerical diagnostic tests (22,27). Therefore, Youden index was employed in our study in order to find out the cut-off value that represents the maximum potential effectiveness of albumin and NLR.…”

Section: Data Collectionmentioning

confidence: 99%

“…Each patient had an ANS score ranging from 0 to 2. Recently, several studies demonstrated ANS played an important role in predicting complication and prognosis for patients with oral and gastric cancer (22)(23)(24). However, there is still no study assessing whether the simple and novel ANS has predictive ability for complications in patients with PD.…”

Section: Introductionmentioning

confidence: 99%

“…Nomogram is a statistical tool employed to predict an individual's particular outcome, which has been widely used in clinical practice (22,24,25). The aim of this study was to find out the most predictive inflammatory marker and subsequently combine it with other perioperative variables to develop a nomogram to predict the likelihood of postoperative complications after PD, using data from one of the high-volume (>60 PDs/year) pancreatic centers in China (13,26).…”

Section: Introductionmentioning

confidence: 99%

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Nomogram based on albumin and neutrophil-to-lymphocyte ratio for predicting postoperative complications after pancreaticoduodenectomy

Huang

Wang

et al. 2021

Gland Surg

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Background: The aim of this study was to identify a preoperative inflammatory marker with the most predictive value for postoperative complications after pancreaticoduodenectomy (PD). We then combined it with other perioperative variables to construct and validate a nomogram for complications after PD.Methods: A total of 223 patients who received PD from January 2014 to July 2019 at a high-volume (>60 PDs/year) pancreatic centers in China were included in this retrospective study. All of the PDs were performed by the same surgeon who is beyond the learning curve with more than 100 PDs over the previous 3 years before 2014. 15 preoperative inflammatory markers were collected, including neutrophils, lymphocytes, high-sensitivity C-reactive protein and lactic dehydrogenase. The inflammatory markers' predicting abilities for complications were analyzed by calculating the values of an area under the curve (AUC).The complications included surgical complications (such as pancreatic fistula, delayed gastric emptying and bile leakage) and medical complications (such as sepsis, pneumonia, urinary tract infection, acute heart failure and acute liver failure) in this study. Univariable and multivariable logistic regression analyses were performed to investigate the perioperative features for independent risk factors for complications after PD. Nomograms with or without the most predictive inflammatory for complications were subsequently developed based on multivariable logistic regression using Akaike information criterion. Nomograms' performance was quantified and compared in terms of calibration and discrimination. We studied the utility of the nomograms using decision curve analysis.Results: The albumin/ NLR score (ANS) exhibited the highest AUC value (0.616) for predicting postoperative complications. ANS and approach method were identified as independent risk factors for complications. The nomogram with ANS had higher C-index (0.725) and better calibration. The NRI compared between nomograms was 0.160 (95%

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Section: Data Collectionsupporting

confidence: 91%

Section: Data Collectionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Nomogram based on albumin and neutrophil-to-lymphocyte ratio for predicting postoperative complications after pancreaticoduodenectomy

Huang

Wang

et al. 2021

Gland Surg

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“…Nomogram is a practical tool for clinicians to predict each patient's outcome (15,16). This study aimed to identify risk factors for mandatory ICU admission and use them to develop a nomogram for predicting mandatory ICU admission after gastrectomy for gastric cancer.…”

Section: Introductionmentioning

confidence: 99%

Nomogram for predicting mandatory ICU admission after gastrectomy for gastric cancer

Huang¹,

Han²,

Xia³

et al. 2021

Ann Palliat Med

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Background: This study aimed to identify risk factors that were associated with mandatory intensive care unit (ICU) admission after gastrectomy for gastric cancer. We then employed these risk factors to construct and validate a nomogram for predicting mandatory ICU admission after gastrectomy, which may identify those who require ICU indeed and improve ICU utilization.Methods: A number of 999 gastric cancer patients undergoing gastrectomy from January 2010 to June 2019 were included in the retrospective study. Forty-three patients were classified into mandatory ICU admission groups, and the remaining 956 patients were allocated into the no need for ICU admission group. The candidate variables, including patient demographic characteristics, preoperative laboratory tests and surgical variables, were compared between the two groups. We then carried out univariate and multivariate logistic regression analyses to find out risk factors for mandatory ICU admission. In order to develop the predictive model, we used Akaike information criterion (AIC) to select risk factors via a step-down backward process from the multivariate regression model.

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Controlled low central venous pressure maintenance level during laparoscopic hepatectomy negatively associated with PHLF incidence: a retrospective propensity score matching study

Liu,

Yang,

Yang

et al. 2024

Surg Endosc

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Development and validation of a nomogram incorporating selected systemic inflammation-based prognostic marker for complication prediction after vascularized fibula flap reconstruction

Cited by 15 publications

References 39 publications

Nomogram based on albumin and neutrophil-to-lymphocyte ratio for predicting postoperative complications after pancreaticoduodenectomy

Nomogram based on albumin and neutrophil-to-lymphocyte ratio for predicting postoperative complications after pancreaticoduodenectomy

Nomogram for predicting mandatory ICU admission after gastrectomy for gastric cancer

Controlled low central venous pressure maintenance level during laparoscopic hepatectomy negatively associated with PHLF incidence: a retrospective propensity score matching study

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