Development and validation of a RP-HPLC method for simultaneous determination of salicin and eight flavonoids in leaves of<i>Salix Matsudana</i>Koidz

Li, W.; Shi, LH; Han, Li; Zhang, J.

doi:10.1556/achrom.25.2013.4.11

Cited by 3 publications

(4 citation statements)

References 17 publications

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“…Salix contains a wide variety of flavonoids, which are distinctive for each species, as flavones, flavonols, flavanones, dihydroflavonols, isoflavones, chalcones, dihydrochalcones, flavan-3-ols and anthocyanins (Nasudari et al, 1972;Pobł ocka-Olech and Krauze-Shao et al, 1989;Du et al, 2004;Zeid, 2006;Jü rgenliemk et al, 2007;Baranowska, 2008;Freischmidt et al, 2010;Li et al, 2013). Data are summarized in Supplementary Table S1 and the structures are presented in Figure 1.…”

Section: Flavonoidsmentioning

confidence: 99%

Phytochemistry, Pharmacology and Medicinal Uses of Plants of the Genus Salix: An Updated Review

et al. 2021

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The Willows (genus Salix), with more than 330–500 species and 200 hybrids, are trees, shrubs or prostrate plants that are widely distributed in Africa, North America, Europe, and Asia. The genus is traditionally used in folk medicine and represents a valuable source of biologically active compounds among them salicin, a prodrug for salicylic acid. Altogether, 322 secondary metabolites were characterized in the genus including flavonoids 94) (flavonols, flavones, flavanones, isoflavones, flavan-3-ols (catechins and procyanidins), chalcones, dihydrochalcone, anthocyanins, dihydroflavonols), phenolic glycosides (76), organic acids (28), and non-phenolic glycosides (17), sterols and terpenes (17), simple phenolics 13) and lignans 7) in addition to volatiles and fatty acids (69). Furthermore, willows exert analgesic, anti-inflammatory, antioxidant, anticancer, cytotoxic, antidiabetic, antimicrobial, antiobesity, neuroprotective and hepatoprotective activities. The current review provides an updated summary of the importance of willows, their chemical composition and pharmacological activities.

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Section: Flavonoidsmentioning

confidence: 99%

Phytochemistry, Pharmacology and Medicinal Uses of Plants of the Genus Salix: An Updated Review

et al. 2021

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“…The distribution of various flavonoids across different species of the Salix genus, including their occurrence in different plant parts such as leaves, roots, and bark [10,11].…”

Section: Flavonoidsmentioning

confidence: 99%

“…: Methanol extract of S. matsudana Koidz. leaves showed inhibitory activities against cyclooxygenases (COX-1 and COX-2) due to the presence of matsudone, luteolin 7-Oglucoside, and 4′,7-dihydroxyflavone [43].…”

Section: Anti-inflammatory Activitymentioning

confidence: 99%

Multiple Natural Approaches of Salix alba

Marina,

Amalia,

Nicoleta

et al. 2024

Preprint

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The Willows, belonging to the genus Salix, encompass a vast array of species and hybrids, totaling between 330 to 500 species along with approximately 200 hybrids. These plants are found across continents such as Africa, North America, Europe, and Asia, exhibiting diverse forms ranging from trees to shrubs and prostrate plants. Traditionally, Willows have been utilized in folk medicine due to their rich reservoir of biologically active compounds, with salicin being a notable example, serving as a prodrug for salicylic acid.The chemical composition of Willows is highly diverse, with 322 secondary metabolites identified thus far. These include various classes such as flavonoids (94 types encompassing flavonols, flavones, flavanones, isoflavones, flavan-3-ols like catechins and procyanidins, chalcones, dihydrochalcone, anthocyanins, and dihydroflavonols), phenolic glycosides (76), organic acids (28), non-phenolic glycosides (17), sterols, and terpenes (17), simple phenolics (13), lignans (7), as well as volatiles and fatty acids (69). This rich chemical di-versity underpins the various pharmacological activities exhibited by Willows. The pharmacological properties attributed to Willows are extensive and include analgesic, an-ti-inflammatory, antioxidant, anticancer, cytotoxic, antidiabetic, antimicrobial, antiobesity, neuroprotective, and hepatoprotective effects. These properties make Willows a subject of con-siderable interest in the fields of medicine and pharmacology. In summary, Willows represent a valuable natural resource with a diverse chemical composition and a wide range of pharmacological activities. This study aimed to enhance our comprehension of the medicinal characteristics of willow bark extract, focusing on its antimicrobial properties. This investigation holds significance in validating the traditional usage of willow bark and investi-gating its potential utility in contemporary medicine.

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“…Recent years have witnessed the rapid development of certain modern techniques, for instance, HPLC‐UV and HPLC‐DAD, which have been verified as powerful and excellent approaches for the characterization and determination of constituents described above in TCM or TCMFs (Li, Shi, Han, & Zhang, ; Wei, Yang, Chen, Wang, & Cui, ; Yang et al, ; Yang, Yan, Mo, Li, & Wang, ; Zhou et al, ). Despite all the advantages, the HPLC method has a number of drawbacks such as low sensitivity, limited suitability and is time‐consuming, which seriously restricts its application in multi‐ingredient analysis.…”

Section: Introductionmentioning

confidence: 99%

A novel UPLC‐MS/MS method for simultaneous determination of 10 effective constituents in the Jixingshizhen preparation

Cui

Sun

Wang

et al. 2016

Biomedical Chromatography

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A novel, reliable and reproducible UPLC-MS/MS method was developed and validated to determine simultaneously the 10 bioactive constituents (baicalin, baicalein, wogonoside, wogonin, luteoloside, dictamnine, fraxinellone, obacunone, geniposidic acid and glycyrrhizic acid) in Jixingshizhen (JXSZ) preparation. Briefly, chromatographic separation was achieved on a Waters BEH C18 column with gradient elution employing a mobile phase composed of acetonitrile and 0.1% formic acid at a flow rate of 0.3 mL/min. All analytes containing internal standard (verapamil) were detected without interference in the multiple reaction monitoring mode with positive electrospray ionization. Further, a comprehensive validation of the method was rigorously executed according to the guidelines of the International Conference on Harmonization and Chinese Pharmacopoeia (2015 Edition). The results indicated that the validated method afforded desired linearity, precision, accuracy, sensitivity and stability. At length, the newly established method was successfully applied to quantify the 10 effective ingredients in JXSZ granules from different production batches, indicating the proposed method in this paper was particularly preferable for the routine analysis of JXSZ preparation as well as the quality control, particularly in situations where high sample throughput and fast analytical speed are required.

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Development and validation of a RP-HPLC method for simultaneous determination of salicin and eight flavonoids in leaves ofSalix MatsudanaKoidz

Cited by 3 publications

References 17 publications

Phytochemistry, Pharmacology and Medicinal Uses of Plants of the Genus Salix: An Updated Review

Phytochemistry, Pharmacology and Medicinal Uses of Plants of the Genus Salix: An Updated Review

Multiple Natural Approaches of Salix alba

A novel UPLC‐MS/MS method for simultaneous determination of 10 effective constituents in the Jixingshizhen preparation

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