Development and validation of an easy multiresidue method for the determination of multiclass pesticide residues using GC–MS/MS and LC–MS/MS in olive oil and olives

Anagnostopoulos, Chris; Miliadis, G. E.

doi:10.1016/j.talanta.2013.03.051

Cited by 102 publications

(52 citation statements)

References 12 publications

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“…However, in this study recoveries of all targeted analytes ranged from 70% to 130%, obtained both by citrate-buffered and unbuffered QuEChERS versions with no obvious difference between those two methods [46]. An easy multiresidue method for the determination of residues of insecticides, fungicides and herbicides of 32 different chemical groups using GC-MS/MS and LC-MS/MS in olive oil and olives was developed and validated by Anagnostopoulos and Miliadis [47]. Authors found freezing-out step as critical for fat removal.…”

Section: Quechers In Pesticides Analysismentioning

confidence: 72%

“…All investigated pesticides had recoveries in the range of 70-120%, with relative standard deviation values less than 20-25%. Authors applied this method to 262 samples of olive oil and olives from the Greek market, 7% of which were found positive for the presence of pesticide [47]. Lee et al described a new QuEChERS method referred as the dry ice-partitioning QuEChERS method for the determination of 168 pesticides in paprika using tandem mass spectrometry [48].…”

Section: Quechers In Pesticides Analysismentioning

confidence: 99%

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A review of recent developments and trends in the QuEChERS sample preparation approach

2015

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Abstract:A comprehensive review is presented on the recent developments and trends in the QuEChERS (quick, easy, cheap, effective, rugged, and safe) sample preparation approach. This technique involves liquidliquid partitioning using acetonitrile and purifying the extract using dispersive solid-phase extraction (d-SPE). Originally, the QuEChERS was introduced for pesticides residues analysis in high moisture fruits and vegetables, but more recently it is gaining significant popularity in the analysis of broad spectrum of analytes in huge variety of samples. The wide range of the technique applications is possible due to introducing various modifications based on the use of different extraction solvent and salt formulation and buffer additions for salting-out partitioning step and the application of various d-SPE sorbents for clean-up step. Therefore, the QuEChERS approach is useful for analysis of, among others pesticides, veterinary drugs and other pharmaceuticals, mycotoxins, polycyclic aromatic hydrocarbons (PAHs), dyes, acrylamide, synthetic musks and UV filters, bisphenols, polybrominated diphenyl ethers and other flame retardants, endocrine disruptors, and other chemical compounds. Thanks to the QuEChERS approach, high-throughput multiresidue methods operate in a routine contaminant control of food products, feedstuff, and environmental samples.

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Section: Quechers In Pesticides Analysismentioning

confidence: 72%

Section: Quechers In Pesticides Analysismentioning

confidence: 99%

A review of recent developments and trends in the QuEChERS sample preparation approach

2015

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“…For the gradient elution two solvents were used: A=0.1% (v/v) HCOOH, 20% (v/v) methanol in water and B=0.1% (v/v) HCOOH and 5 mM HCOONH4 in methanol. The gradient elution program is shown in Table 1 (Anagnostopoulos and Miliadis, 2013). The column temperature was 40 o C, the flow rate 0.25 mL/min and the sample volume 5 μL, was diluted with 20 μL of water and injected into the autosampler, in order to have the same composition of the injected sample with the initial mobile phase.…”

Section: Methodsmentioning

confidence: 99%

Carry over effect in pesticide residues analysis by LC - MS/ MS

Miliadis¹,

Malatou

Tsiantas³

et al. 2018

J Hellenic Vet Med Soc

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The Carry over effect, i.e. the appearance of a peak in the chromatogram of a blank analysis due to sample remaining from the previous analysis, was studied. The study was conducted for pesticide residues analysis by LC-MS/MS. In total 128 pesticides that belong to 13 different chemical classes were analyzed in order to investigate the cases that the effect is significant; i.e. a peak higher than 1% of the peak of the previous chromatogram appears. Carry over was found for 32 of the 128 studied pesticides (25%), at concentration levels between the LOD and 0.167 μg/mL. For 28 out of the 32 substances, more than two injections of a blank sample were required, as to reduce the effect significantly. Compounds presenting Carry over effect were mainly non-polar with logkow values between 4 and 7, characterized with very low water solubility, between 0.001 mg/L and 2 mg/L. On the contrary, the vapor pressure did not seem to be obviously related to the effect, as the substances presenting Carry over had various vapor pressure values, from 10-12 to 0.2 mP.

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“…Hajslova and Zrostlikova (2003) reported that the positive matrix effects are stronger for pesticide molecules with specific function groups, i.e., organophosphates, carbamates, imidazoles, and benzimidazoles. According to Anagnostopoulos and Miliadis (2013), who have developed a method enabling determination of 32 different chemical groups of pesticides in samples of olive oil and olives, a considerable impact of the matrix effect was observed for most analytes from such chemical classes as carbamates, triazoles, or neonicotinoids, whereas no significant matrix effect was observed for organophosphate insecticides. In turn, Giacinti et al (2016) have observed a negative matrix effect for chlorpyrifos of the organophosphate group, boscalid of anilides, and pirimicarb of the carbamate group in their studies on determination of pesticide residues in apple skin samples.…”

Section: Optimization Of Cleanup Conditionsmentioning

confidence: 99%

Liquid Chromatographic MS/MS Analysis of a Large Group of Insecticides in Honey by Modified QuEChERS

2018

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The analytical tool for analysis of pesticide residues in honey must still be improved. Therefore, a sensitive, selective, rapid, and reliable analytical method for the analysis of pesticide residue belonging to 29 different classes at very low concentration levels was developed. Over 130 insecticides were extracted from the honey matrix using different amounts of sample, concentrations of the extraction solvent, and cleanup sorbents. Acceptable extraction recoveries accounting for matrix effect were obtained using the cleanup sorbent combination chitosan/aluminum oxide/C8 (200/200/200 mg) and 1% FA in ACN. Determinations were made by liquid chromatography-tandem mass spectrometry (LC-MS/MS). For most compounds, the recoveries range from 70 to 120%, with relative standard deviations < 20%. Linear correlation coefficients (r2) were higher than 0.99 at concentration levels of 0.001-0.100 mg kg−1. A positive matrix effect was observed for up to 95% of organophosphates and 43% of pyrethroids and a negative effect for 37% of neonicotinoids. This work showed that the presented method is convenient and reliable for quick monitoring of insecticides in honey samples.

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Development and validation of an easy multiresidue method for the determination of multiclass pesticide residues using GC–MS/MS and LC–MS/MS in olive oil and olives

Cited by 102 publications

References 12 publications

A review of recent developments and trends in the QuEChERS sample preparation approach

A review of recent developments and trends in the QuEChERS sample preparation approach

Carry over effect in pesticide residues analysis by LC - MS/ MS

Liquid Chromatographic MS/MS Analysis of a Large Group of Insecticides in Honey by Modified QuEChERS

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