Development and validation of an HPLC-UV method for iodixanol quantification in human plasma

Determination of iodinated X-ray contrast agents in pharmaceutical formulations and artificial urine samples by differential pulse voltammetry

“…LODs reported for IOP, ION and DTZA in the literature ranged from 0.02 to 1.43 mg L À1 . [17][18][19][20][21][22][23][26][27][28][29][30][31][32][33][34][35][36][37][38][39][40] The LOD and LOQ values are summarized in Table 4. Both LOD and LOQ values conrmed the sensitivity of the proposed methods.…”

“…14 It is used as a contrast agent during coronary angiography and CT imaging of the brain and body. 15,16 Determination of ION in human and animal plasma, urine and serum has been reported using high-performance liquid chromatography (HPLC) with ultraviolet detection (UV) 3,[17][18][19][20] and tandem mass spectrometry (MS/ MS) used as detection techniques. 21 The colorimetric method for determination of iodixanol in biological uids was also developed.…”

Development and Application of a Liquid Chromatography-Mass Spectrometry Method for Residual Iodixanol Quantification in AAV-Based Gene Therapy Product Development

“…[1][2][3] AAVs are small icosahedral non-enveloped viruses with singlestranded DNA genome encapsulated in a protein capsid shell. There have been 13 AAV serotypes reported. 4 Cesium chloride-and iodixanol-based density gradients are the core step among the most common purification methods for serotype-independent AAV.…”

The novel technique of vapor pressure analysis to monitor the enzymatic degradation of PHB by HPLC chromatography

“…simplicity, ease of operation and convenience, UV-VIS spectrophotometry is a frequently used qualitative and quantitative analytical method in the field of biotechnology [1][2][3][4][5], but also in liquid chromatography [4][5][6][7][8][9][10][11][12][13][14][15][16]. However, besides their advantages, UV-VIS detectors have some drawbacks as well.…”