Development and Validation of GC-ECD Method for the Determination of Metamitron in Soil

Abstract

This paper aims at developing and validating a convenient, rapid, and sensitive method for estimation of metamitron from soil samples.Determination andquantification was carried out by Gas Chromatography on microcapillary column with an Electron Capture Detector source. The compound was extracted from soil using methanol and cleanup by C-18 SPE. After optimization, the method was validated by evaluating the analytical curves, linearity, limits of detection, and quantification, precision (repeatability and intermediate precision), and accuracy (recovery). Recovery values ranged from 89 to 93.5% within 0.05- 2.0 µg L−1 with average RSD 1.80%. The precision (repeatability) ranged from 1.7034 to 1.9144% and intermediate precision from 1.5685 to 2.1323%. Retention time was 6.3 minutes, and minimum detectable and quantifiable limits were 0.02 ng mL−1 and 0.05 ng g−1, respectively. Good linearity (R 2 = 0.998) of the calibration curves was obtained over the range from 0.05 to 2.0 µg L−1. Results indicated that the developed method is rapid and easy to perform, making it applicable for analysis in large pesticide monitoring programmes.

Appraisal for Edible Use of Vegetable Crops Cultivated in Egypt after Treatment with Selected Insecticides and Fungicides: Insights of Dissipation Rates and Pre-harvest Intervals

“…The assigned chromatographic conditions gave the best results regarding selectivity and accuracy. Both methods are considered to be economic and suitable for routine low-cost analysis when compared to other hyphenated methods such as GC-MS, GC TQ-MS and LC-MS/MS [43][44][45][46] .…”

Determination of Resmethrin in Corn Silk Matrix by Gas Chromatography-Flame Ionization Detector (GC-FID)

“…Chromatography is a frequently used technique for the separation and determination of pesticides and other pollutants and is classified into liquid chromatography (LC) [15] and gas chromatography (GC) [16] according to the physical properties of the mobile phase used [17]. GC which is used as an effective separation of volatile organic compounds, is combined with different detectors such as thermal conductivity detector (TCD) [18], mass spectrometry (MS) [19], electron capture detector (ECD) [20], flame photometric detector (PID) [21], nitrogen phosphorus detector (NPD) [22] and flame ionization detector (FID) [18] for the determination of compounds with high accuracy and precision. A hydrogen flow mixed with carrier gas is used in the FID system.…”