The current situation is the low character of students, so brawls and violence often occur in various layers of society. The present study is aimed at analyzing the effectiveness of the science learning model in improving the character and scientific literacy of junior high school students. The research is a quasi-experimental design in the form of a posttest-only control design. The study sample was 158 people. A questionnaire and test were used for the character and scientific literacy variable data collection. Descriptive analysis and inferential analysis were used to analyze the post-test data. The descriptive analysis involved the mean, standard deviation, and variance. Inferential statistical analysis was done with the MANOVA test. The analysis results showed that the F value for Pillae Trace, Wilk Lambda, Hotelling Trace, and Roy's Largest Root had significantly less than 0.001, which means all are significant. Therefore, the study indicates that the science learning model containing Balinese local wisdom is effective on character and scientific literacy. Thus, this learning is recommended as a solution that can be used as an innovative learning model.