Development of a colorimetric and turn-on fluorescent probe with large Stokes shift for H2S detection and its multiple applications in environmental, food analysis and biological imaging

Lu, Guifen; Duan, Luyao; Meng, Suci; Cai, Peiyang; Ding, Sihan; Wang, Xiaochun

doi:10.1016/j.dyepig.2023.111687

Cited by 98 publications

(10 citation statements)

References 43 publications

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“…Expanding to a tetrasubstituted system, Jiang, Li, and Chen reported 480 (TDBP), which responded to both H 2 S and GSH to generate a fluorescent response that was confirmed in HepG2 cells . Expanding to corrole-based systems, Lu reported the p -chlorophenyl 481 (COR-DNBS), phenyl 482 (DPC-DNBS), and naphthyl 483 (NPC-H 2 S) derivatives in separate publications. − These probes provided a fluorescent response ∼650 nm and were found to be compatible with imaging exogenous H 2 S in HeLa cells. Probe 482 was also shown to react with both H 2 S and N 2 H 4 .…”

Section: Electrophilic H2s Probesmentioning

confidence: 99%

Activity-Based Fluorescent Probes for Hydrogen Sulfide and Related Reactive Sulfur Species

Fosnacht,

Pluth

2024

Chem. Rev.

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Hydrogen sulfide (H 2 S) is not only a well-established toxic gas but also an important small molecule bioregulator in all kingdoms of life. In contemporary biology, H 2 S is often classified as a "gasotransmitter," meaning that it is an endogenously produced membrane permeable gas that carries out essential cellular processes. Fluorescent probes for H 2 S and related reactive sulfur species (RSS) detection provide an important cornerstone for investigating the multifaceted roles of these important small molecules in complex biological systems. A now common approach to develop such tools is to develop "activitybased probes" that couple a specific H 2 S-mediated chemical reaction to a fluorescent output. This Review covers the different types of such probes and also highlights the chemical mechanisms by which each probe type is activated by specific RSS. Common examples include reduction of oxidized nitrogen motifs, disulfide exchange, electrophilic reactions, metal precipitation, and metal coordination. In addition, we also outline complementary activity-based probes for imaging reductant-labile and sulfane sulfur species, including persulfides and polysulfides. For probes highlighted in this Review, we focus on small molecule systems with demonstrated compatibility in cellular systems or related applications. Building from breadth of reported activity-based strategies and application, we also highlight key unmet challenges and future opportunities for advancing activity-based probes for H 2 S and related RSS.

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Section: Electrophilic H2s Probesmentioning

confidence: 99%

Activity-Based Fluorescent Probes for Hydrogen Sulfide and Related Reactive Sulfur Species

Fosnacht,

Pluth

2024

Chem. Rev.

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“…However, this is constrained by the cross-reactivity with peptides that share structural similarities, which obstructs the accurate quantification of Goserelin in plasma. Despite the fact that there are several analytical techniques for the quantitative or qualitative Goserelin determination, such as liquid chromatography-electrospray ionization mass spectrometry (LC-ESI-MS), radioimmunoassay, capillary zone electrophoresis (CZE)-UV/MS, CE hydrogen deuterium exchange-MS (CE-H/D-MS), multiple-injection CZE (MICZE) and quadrupole time-of-flight MS (Q-TOF MS), as well as fast atom bombardment-MS (FAB-MS) (7)(8)(9)(10)(11)(12)(13), these studies have often focused on medicinal formulations, degradation products, and crude synthesized peptide combinations. All of these present methods are not employed for the determination of Goserelin in a possible pharmaceutical dosage form and usually employed to quantify illegal substances in biological fluids.…”

Section: Lhrh (Luteinizing Hormone-releasing Hormone) Analoguementioning

confidence: 99%

Electrochemical DNA-nano biosensor for the detection of Goserelin as anticancer drug using modified pencil graphite electrode

Laylani,

Al-dolaimy,

Altharawi

et al. 2024

Front. Oncol.

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Goserelin is an effective anticancer drug, but naturally causes several side effects. Hence the determination of this drug in biological samples, plays a key role in evaluating its effects and side effects. The current studies have concentrated on monitoring Goserelin using an easy and quick DNA biosensor for the first time. In this study, copper(II) oxide nanoparticles were created upon the surface of multiwalled carbon nanotubes (CuO/MWCNTs) as a conducting mediator. The modified pencil graphite electrode (ds-DNA/PA/CuO/MWCNTs/PGE) has been modified with the help of polyaniline (PA), ds-DNA, and CuO/MWCNTs nanocomposite. Additionally, the issue with the bio-electroanalytical guanine oxidation signal in relation to ds-DNA at the surface of PA/CuO/MWCNTs/PGE has been examined to determination Goserelin for the first time. It also, established a strong conductive condition to determination Goserelin in nanomolar concentration. Thus, Goserelin’s determining, however, has a 0.21 nM detection limit and a 1.0 nM-110.0 µM linear dynamic range according to differential pulse voltammograms (DPV) of ds-DNA/PA/CuO/MWCNTs/PGE. Furthermore, the molecular docking investigation highlighted that Goserelin is able to bind ds-DNA preferentially and supported the findings of the experiments. The determining of Goserelin in real samples has been effectively accomplished in the last phase using ds-DNA/PA/CuO/MWCNTs/PGE.

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“…Azole pesticides get adsorbed on MPs via bonds hydrogen bonding, hydrophobic interaction, and halogen bonding ( Fig. 1 d) [ 141 , 142 ]. Electrostatic interactions and surface complexation are the principal mechanisms by which heavy metal ions like those of Pb, Cd, As, Cr, etc.…”

Section: Mechanism Of Interaction Between Mps and Various Endocrine D...mentioning

confidence: 99%

Detrimental consequences of micropolymers associated plasticizers on endocrinal disruption

Saha,

Kumari,

Ghosh

et al. 2024

Materials Today Bio

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Development of a colorimetric and turn-on fluorescent probe with large Stokes shift for H2S detection and its multiple applications in environmental, food analysis and biological imaging

Cited by 98 publications

References 43 publications

Activity-Based Fluorescent Probes for Hydrogen Sulfide and Related Reactive Sulfur Species

Activity-Based Fluorescent Probes for Hydrogen Sulfide and Related Reactive Sulfur Species

Electrochemical DNA-nano biosensor for the detection of Goserelin as anticancer drug using modified pencil graphite electrode

Detrimental consequences of micropolymers associated plasticizers on endocrinal disruption

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