Development of a cost-effective modular pixelated NaI(Tl) detector for clinical SPECT applications

Rozler, Michael; Liang, Haoning; Chang, Wei

doi:10.1109/tns.2012.2210908

Cited by 17 publications

(8 citation statements)

References 15 publications

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“…Detector: The desired curved shape of the system, in addition to the need to minimize the dead area at the edges of the detectors, led to the choice of pixelated detectors, which are made of 1-cmthick NaI(Tl) crystal scintillator [4]. The pixel pitch is 2.5 mm (transversely) by 3 mm (axially), and there are 36 (transverse) by 56 (axial) pixels.…”

Section: The C-spect Projectmentioning

confidence: 99%

C-SPECT, a novel cardiac single-photon emission computed tomography system

Strologas¹,

Rozler²,

Metzler³

et al. 2017

Proceedings of 38th International Conference on High Energy Physics — PoS(ICHEP2016)

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Single-photon emission computed tomography (SPECT) is the leading medical-imaging method for the study myocardial perfusion, which is important for the diagnosis and treatment of coronary-artery disease, the number-one killer in the western world. C-SPECT is a proposed dedicated cardiac SPECT system designed to achieve at least double the geometric efficiency compared to general-purpose dual-head gamma cameras, for the same resolution. This improvement can be used to reduce patient radiation dose, achieve fast or dynamic imaging, and enhance the quality of images. The system consists of stationary detector modules of pixelated NaI(Tl), a slit-slat collimator with interchangeable slits and collapsible slats, and an integrated CT for attenuation correction. The collimator slits provide pinhole collimation in the transverse plane, whereas the slats offer parallel-beam collimation in the axial direction. The adaptive power of the collimator allows us to adjust, in situ, the sensitivity and resolution depending on the imaging task. This way, superior reconstructed-image resolution could be achieved if the system operates with the usual geometric efficiency of the industry's benchmark. The system gantry wraps around patients' left-front thorax and provides a transverse projection minification of ∼ 50%, for a maximal number of minimally-overlapping projections, given the limitations from the spatial resolution of the pixelated detector. We present the design principles and preliminary imaging performance using three-dimensional iterative reconstruction with resolution recovery and data from the newly-built laboratory prototype as well as Monte-Carlo (MC) simulations of the full system.

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Section: The C-spect Projectmentioning

confidence: 99%

C-SPECT, a novel cardiac single-photon emission computed tomography system

Strologas¹,

Rozler²,

Metzler³

et al. 2017

Proceedings of 38th International Conference on High Energy Physics — PoS(ICHEP2016)

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“…To improve positioning linearity near the edges, several solutions have been proposed over the years. In some cases, PMTs were extended over the edges of the scintillator both for continuous crystals [6] and pixelated or semi-pixelated scintillators [7][8][9]. However, in MP-MBT there is no room for such a placement of PMTs since the scintillator extends till the patient bed.…”

Section: Introductionmentioning

confidence: 99%

Novel light-guide-PMT geometries to reduce dead edges of a scintillation camera

et al. 2018

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“…Axially, the modules are 200 mm long, requiring a total of 121 PMTs for the entire 13-module detector system. Previously, we evaluated [9] the performance potential of our approachof by measurements of a small test detector. We worked with Saint Gobain [10], which built a small test section of C-SPECT's planned detector system.…”

Section: Introductionmentioning

confidence: 99%

A cost-effective high-resolution modular pixelated clinical SPECT detector based on small NaI (Tl) pixels with medium-size single-anode PMTs, utilizing spatial modulation of scintillation light output

Rozler

Chang

2012

2012 IEEE Nuclear Science Symposium and Medical Imaging Conference Record (NSS/MIC)

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The current trend toward SPECT systems dedi cated to imaging specific organs has created new pressures to improve gamma camera performance. A number of designs rely on projection minification to increase system sensitivity by acquiring multiple non-overlapping simultaneous views, placing stringent requirements on detector intrinsic spatial resolution (ISR). Curved detector geometries require modular assemblies, making monolithic slab detectors impractical due to their large dead areas at the edges. Previously, we described a modular detector based on a scintillator block comprised of 2.75 x2.75 x 10 mm 3 NaI(Tl) pixels in a 3 x 3 mm pitch and decoded by an array of 51 mm diameter single-anode PMTs. The event positioning accuracy of the curved detector, averaged over its entire area, exceeds that of a hypothetical monolithic slab detector with 2.75 mm ISR. To reduce the pixel size/pitch and thus increase linear sampling in the transaxial dimension (the dimension along which the detector is curved and minification is applied), we introduce scintillation light output modulation between neighboring pixels. A series of narrow absorbing stripes is applied at the exit surface of every other pixel column, producing a modulation in light output between adjacent pixels and allowing the use of energy discrimination to more effectively assign events to the correct pixel. Compared to the 3x3 mm pitch modules, our new detector, with 2.25 x2.75 x 10 mm 3 NaI(Tl) pixels (2.5 x 3 mm pitch), achieves the same event positioning performance in terms of the average event positioning error, while yielding 10.3% energy resolution. This translates to an improvement in linear sampling, without any loss in positioning accuracy (and, thus, effective spatial resolution), a modest energy resolution degradation. accomplished without a cost increase.

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Development of a cost-effective modular pixelated NaI(Tl) detector for clinical SPECT applications

Cited by 17 publications

References 15 publications

C-SPECT, a novel cardiac single-photon emission computed tomography system

C-SPECT, a novel cardiac single-photon emission computed tomography system

Novel light-guide-PMT geometries to reduce dead edges of a scintillation camera

A cost-effective high-resolution modular pixelated clinical SPECT detector based on small NaI (Tl) pixels with medium-size single-anode PMTs, utilizing spatial modulation of scintillation light output

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