Development of a fast method for the isolation of triterpene saponins from Actaea racemosa

Discovery of Diverse Sesquiterpenoids from Crossiella cryophila through Genome Mining and NMR Tracking

“…15 The mature polycyclic terpenoids often possess an isolated double bond or, in some cases, lack it entirely, leading to weak UV absorption that poses challenges for their detection using variable wavelength or diode array detection, a tracking method widely used in natural product discovery. 16 On the other hand, the utilization of DMAPP and IPP precursors also results in the incorporation of multiple methyl groups into the terpenoid structures. These methyl protons, with chemical shifts often ranging from δ H 0.60 to 1.85 ppm, in the 1 H NMR spectrum, represent distinct and characteristic signals specific to terpenoids (Figure 1B).…”