Development of a gamma camera based on an 8&amp;#x00D7;8 array of LaBr&lt;inf&gt;3&lt;/inf&gt;(Ce) scintillator pixels coupled to a 64-channel multi-anode PMT

Kubo, H.; Hattori, K.; Ida, Chihiro; Iwaki, S.; Kabuki, S.; Kurosawa, Shunsuke; Miuchi, K.; Nagayoshi, T.; Nishimura, H.; Okada, Yoko; Orito, R.; Takada, Atsushi; Tanimori, T.; Tsuchiya, K.; Ueno, Katsunori

doi:10.1109/nssmic.2007.4437127

Cited by 8 publications

(9 citation statements)

References 34 publications

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“…Moreover, μ-TPC can remove the neutron [14]. The scattered gamma ray is caught by the second detector, which consists of LaBr 3 pixel scintillator arrays (PSAs) and 64 ch multi-anode photomultiplier tubes (Hamamatsu H8500) [15]. We use five LaBr 3 :Ce PSAs; pixel size of three arrays are 6 × 6 × 20 mm 3 and 4 array is 6 × 6 × 15 mm 3 .…”

Section: Electron-tracking Compton Cameramentioning

confidence: 99%

Imaging study of a phantom and small animal with a two-head electron-tracking Compton gamma-ray camera

Kabuki

Kimura

Amano

et al. 2010

IEEE Nuclear Science Symposuim &Amp; Medical Imaging Conference

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Section: Electron-tracking Compton Cameramentioning

confidence: 99%

Imaging study of a phantom and small animal with a two-head electron-tracking Compton gamma-ray camera

Kabuki

Kimura

Amano

et al. 2010

IEEE Nuclear Science Symposuim &Amp; Medical Imaging Conference

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Section: Electron-tracking Compton Cameramentioning

confidence: 99%

Imaging reagents study for nuclear medicine using an electron-tracking Compton gamma-ray camera

Kabuki

Kimura

Amano

et al. 2009

2009 IEEE Nuclear Science Symposium Conference Record (NSS/MIC)

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Fig 1. (A): Schematic view of the ETCC. The straight line is the electron track; the wavy line is the initial and scattered gamma ray. (B): Photograph of the ETCC. System size including all electronics is 180 × 60 ×100 cm 3 . 100cm Scintillator μPIC μTPC (A) 180cm 60cm (B)γ Abstract-We have developed an electron-tracking Compton camera (ETCC) for new imaging reagents study. Energy limitation of gamma camera is major problem for this study. However, our ETCC has a wide energy dynamic range (200-1300 keV). In this paper, we show the results of imaging reagent study as follows: (1) F-18-FDG (511 keV) and I-131-MIBG (364 keV) simultaneous imaging for double clinical tracer imaging, (2) Zn-65-porphyrin (1116 keV) imaging for high energy gamma-ray imaging and, (3) middle size animal imaging (rabbit). Also we studied the improvement for the camera system.

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“…In 2007, a new scintillator, LaBr3 was introduced to 10cm cube ETCC instead of GSO pixel crystal arrays [15]. La Br3 is a quite promising scintillator for gamma ray detection due to its good light-emission efficiency ("'60photons/keV) and a fast decay time of ,,-,20ns.…”

Section: Performance Of Etccmentioning

confidence: 99%

Development of Electron tracking Compton Camera based on micro pixel gas detector and its application for medical imaging

Tanimori

Amano

Hattori

et al. 2008

2008 IEEE Nuclear Science Symposium Conference Record

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We have developed the Electron tracking Compton Camera (ETCC) with reconstructing the 3-D tracks of the scattered electron in Compton process for both gamma-ray astronomy and medical imaging [1-3). By measuring both the directions and energies of a recoil gamma ray and a scattered electron, the direction of the incident gamma ray is determined for an individual photon. Furthermore, a residual measured angle between the recoil electron and scattered gamma ray is powerful for the kinematical background-rejection. For the 3-D tracking of the electrons, the Micro Time Projection Chamber (Jl-TPC) was developed, which consists of a new type of the micro pattern gas detector, or a Micro Pixel Gas Chamber (Jl-PIC). The ETCC consists of this Jl-TPC and the GSO crystal pixel arrays below the~TPC for detecting the recoil gamma rays. The ETCC provided the gamma ray images of point sources between 120keV and --I MeV with the angular resolution of 6 degree (FWHM) at 511keV of 18F ion, respectively. Also the angle of the scattered electron was measured with the resolution of --80 degree.Two mobile ETCCs with 10cm-cube TPC for small animal and 30cm-cube TPC for human body, are now being operated for Medical Imaging test. We have studied the imaging performances using both phantoms and small animals (rats and mice) for conventional radioisotopes of 131 1 and 18 F_FDG. In particular, new ETCC with LaBr3 pixel scintillator provides good images similar to SPECT for 131 1 and human PET for 511keV, respectively, where a clear concentration to tumors in a mouse is observed The 30cm-cube ETCC can get an image for 1m-size length objects in one measurement. Thus, we have carried out several comparisons of our images with those of SPECT and PET. Multi-tracer image using 1-131 and FDG for small animal and the imate for higher energy gamma ray above 511keV for plants using Mn have been carried out successfully. Also several new biomarkers and new radio nuclides were examined to verify the merits of ETCC for medical imaging.

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Development of a gamma camera based on an 8×8 array of LaBr<inf>3</inf>(Ce) scintillator pixels coupled to a 64-channel multi-anode PMT

Cited by 8 publications

References 34 publications

Imaging study of a phantom and small animal with a two-head electron-tracking Compton gamma-ray camera

Imaging study of a phantom and small animal with a two-head electron-tracking Compton gamma-ray camera

Imaging reagents study for nuclear medicine using an electron-tracking Compton gamma-ray camera

Development of Electron tracking Compton Camera based on micro pixel gas detector and its application for medical imaging

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