Transport of carbon dioxide (CO 2 ) via pipeline from the point of capture to a geologically suitable location for either sequestration or enhanced hydrocarbon recovery is a vital aspect of the carbon capture and storage (CCS) chain. This means of CO 2 transport has a number of advantages over other means of CO 2 transport, such as truck, rail, and ship. Pipelines ensure continuous transport of CO 2 from the capture point to the storage site, which is essential to transport the amount of CO 2 captured from the source facilities, such as fossil fuel power plants, operating in a continuous manner. Furthermore, using pipelines is regarded as more economical than other means of CO 2 transportThe greatest challenges of CO 2 transport via pipelines are related to integrity, flow assurance, capital and operating costs, and health, safety and environmental factors. Deployment of CCS pipeline projects is based either on point-to-point transport, in which case a specific source matches a specific storage point, or through the development of pipeline networks with a backbone CO 2 pipeline. In the latter case, the CO 2 streams, which are characterised by a varying impurity level and handled by the individual operators, are linked to the backbone CO 2 pipeline for further compression and transport. This may pose some additional challenges.This review involves a systematic evaluation of various challenges that delay the deployment of CO 2 pipeline transport and is based on an extensive survey of the literature. It is aimed at confidence-building in the technology and improving economics in the long run. Moreover, the knowledge gaps were identified, including lack of analyses on a holistic assessment of component impurities, corrosion consideration at the conceptual stage, the effect of elevation on CO 2 dense phase characteristics, permissible water levels in liquefied CO 2 , and commercial risks associated with project abandonment or cancellation resulting from high project capital and operating costs.2