Development of a high analytical performance-xanthine biosensor based on layered double hydroxides modified-electrode and investigation of the inhibitory effect by allopurinol

A Fast and Direct Amperometric Determination of Hg2+ by a Bienzyme Electrode Based on the Competitive Activities of Glucose Oxidase and Laccase

“…Moreover, a possible accumulation of Hg 2 + may occur by electrostatic interactions within the outer layer composed of negatively charged clay particles [5,14]. This phenomenon should facilitate the GOD inhibition [5,6,18,19] and hence reduce the response time. Figure 2 shows the average percentage of current increase (current increase/ current decrease due to glucose x 100) as a function of Hg 2 + concentration for three biosensors.…”

Electrochemical Biosensors for Drug Analysis

“…A non-exhaustive survey of different enzyme-based biosensors for inhibition studies is reported in Table 6.3 [95][96][97][98][99][100][101][102][103][104][105][106][107][108]. It is worth mentioning that already in 1990, a SPE was used for enzyme immobilization and inhibition studies namely for the assay of theophylline.…”

“…Xanthine oxidase was retained and cross-linked by GA into an anionic clay thinlayer deposited onto a Pt electrode for the determination of allopurinol by its inhibitory action of XOX product formation [98]. A non-exhaustive survey of different enzyme-based biosensors for inhibition studies is reported in Table 6.3 [95][96][97][98][99][100][101][102][103][104][105][106][107][108].…”

The unmediated choline sensor based on layered double hydroxides in hydrogen peroxide detection mode

“…LDHs have been demonstrated as promising materials due to their technological importance in catalysis, separation, optics, medical science, and nanocomposite materials engineering [18][19][20] . LDHs have also been successfully used as attractive enzyme immobilization matrix in our previous work [21][22][23][24][25][26][27][28] . Their unusual intercalation properties were exploited for an easy and biocompatible immobilization of enzyme molecules.…”