With the rapid development of building level and construction technology, high-rise buildings have been adopted more and more, thus becoming an important place for people to work and live. Because of the high height of high-rise buildings, wind load becomes the main resultant force type of high-rise building. However, wind load has great randomness and unpredictability, which has great influence on the stability of high-rise building. This paper first analyses the main characteristics of wind load borne by tall buildings. Then, the common methods of wind-resistant design of high-rise building are summarized in detail. It also points out the existing problems and deficiencies in wind resistance design of high-rise buildings and the countermeasures and suggestions of wind resistance design of high-rise structures. Finally, according to the current research status and existing problems, the future development of wind resistance design is prospected. Results can provide some references for wind resistance design and research of high-rise buildings.