The purpose of this study was to investigate the diagnostic value of color Doppler ultrasound combined with superb microvascular imaging (SMI) in the detection of small renal tumors less than 3 cm treated with Jinkui Shenqi pills. 50 cases were randomly selected from the patients with angioleiomyoma (a kind of small renal tumor) less than 3 cm confirmed by pathological examination and treated in our hospital from January 2018 to January 2020. All patients were treated with Jinkui Shenqi pills. All patients were first detected by color Doppler ultrasound and then by SMI. The results of color Doppler ultrasound were used as the control group, while those of color Doppler ultrasound combined with SMI were used as the experimental group. After that, the specificity, sensitivity, positive and negative detection results, and detection accuracy were compared between the two groups. The specificity and sensitivity in the experimental group were significantly higher than those in the control group, with statistical significance (
P
<
0.05
). The cases of positive and negative detection results in the experimental group were significantly higher than those in the control group, with statistical significance (
P
<
0.05
). The detection accuracy in the experimental group was significantly higher than that in the control group, with statistical significance (
P
<
0.05
). The specificity, sensitivity, positive and negative detection results, and detection accuracy of color Doppler ultrasound combined with SMI in the detection of small renal tumors less than 3 cm treated with Jinkui Shenqi pills were all significantly higher than those of color Doppler ultrasound; therefore, the application of color Doppler ultrasound combined with SMI for the diagnosis of small renal tumors is of high value.